Results 191 to 200 of about 307,044 (299)

Epigenetic Regulation of Aging and its Rejuvenation. [PDF]

MedComm (2020)
An Y, Wang Q, Gao K, Zhang C, Ouyang Y, Li R, Ma Z, Wu T, Zhou L, Xie Z, Zhang R, Wu G.   +11 more
europepmc   +1 more source

Concise Review: Epigenetic Regulation of Hematopoiesis: Biological Insights and Therapeutic Applications [PDF]

, 2017
Chiara Antoniani, Oriana Romano, Annarita Miccio   +2 more
openalex   +1 more source

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

Advanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou, Peilong Lai, Guanjie Peng, Bo Lu, Lizhen Jiang, Xinyue Li, Jinghong Chen, Ladi Mo, Qiong Mao, Haichuan Zhang, Jinxin Fang, Yi Meng, Aochu Liu, Yingyin Gao, Andong Huang, Wenhui Lin, Shiwen Hu, Zerong Guan, Xiaolan Ye, Zhenguo Liu, Liling Jiang, Yueyuan Zheng, Xianping Shi   +22 more
wiley   +1 more source

Epigenetic regulation of cancer stemness. [PDF]

Signal Transduct Target Ther
Galassi C, Manic G, Esteller M, Galluzzi L, Vitale I.   +4 more
europepmc   +1 more source

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

Familial Mediterranean Fever: A Comprehensive Review of Pathogenesis, Genetics, and Epigenetic Regulation. [PDF]

Balkan Med J
Ugurlu S, Kilinc OC, Karacan I, Parlar K.   +3 more
europepmc   +1 more source

MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes [PDF]

, 2018
Marco Witkowski, Termeh Tabaraie, Daniel Steffens, Julian Friebel, Andrea Dörner, Carsten Skurk, Mario Witkowski, Bernd Stratmann, Diethelm Tschoepe, Ulf Landmesser, Ursula Rauch   +10 more
openalex   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Epigenetic AR regulation [PDF]

Nature Reviews Urology, 2017
openaire   +1 more source

Epigenetic Regulation of Neutrophils in ARDS. [PDF]

Cells
Williams JE, Mauya Z, Walkup V, Adderley S, Evans C, Wilson K.   +5 more
europepmc   +1 more source