Results 261 to 270 of about 307,044 (299)

Molecular Insights into Phytochemicals Mediated Epigenetic Regulation in Preclinical Models of Breast Cancer. [PDF]

Drug Des Devel Ther
Pandey P, Alkhathami AG, Saeed M, Alshaghdali K, Kumar S, Tallei TE, Bae H, Park MN, Kumar G, Kim B, Khan F.   +10 more
europepmc   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Resistance of first-line targeted drugs in hepatocellular carcinoma: the epigenetic regulation mechanisms. [PDF]

Cell Death Dis
Qi D, Qin Y, Zhu H, Li Y, Han S.
europepmc   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Epigenetic regulation of airway epithelial barrier dysfunction in pediatric asthma: mechanistic insights and therapeutic potential. [PDF]

Front Med (Lausanne)
Wang Y, Xiang Z, Zhu J.
europepmc   +1 more source

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy. [PDF]

Diabetes Metab Res Rev
Russell-Hallinan A, Karuna N, Lezoualc'h F, Matullo G, Baker H, Bernard M, Devaux Y, Badimon L, Vilahur G, Rieusset J, Derumeaux GA, Watson CJ.   +11 more
europepmc   +1 more source

Beyond the genome: epigenetic regulation of immune responses and T cells in brain tumors. [PDF]

Front Immunol
Sun S, Han Y, Li H, Wang C, Zhou S, Zhang X, Dai S, Peng Y, Wang Z.   +8 more
europepmc   +1 more source

Epigenetic regulation in gynecological cancers: a paradigm shift in immunotherapy strategies. [PDF]

J Exp Clin Cancer Res
Zhao C, Liu Y, Cui Z.
europepmc   +1 more source

Cross-Talk Between Epigenetic Regulation And Mir-17~92 Cluster Expression In Idiopathic Pulmonary Fibrosis (IPF)

, 2011
Duaa Dakhlallah
openalex   +1 more source

Statins and their impact on epigenetic regulation: insights into disease. [PDF]

Front Pharmacol
Tamayo-Trujillo R, Guevara-Ramírez P, Cadena-Ullauri S, Ruiz Pozo VA, Paz-Cruz E, Zambrano AK.   +5 more
europepmc   +1 more source