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Epigenetic regulation of osteoclast differentiation
Annals of the New York Academy of Sciences, 2011Recent studies have uncovered that epigenetic regulation, such as histone methylation and acetylation, plays a critical role in determining cell fate. In particular, the expression of key developmental genes tends to be regulated by trimethylation of histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3).
Tetsuro, Yasui +3 more
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PARP and Epigenetic Regulation
2008In the post-genome era attention is being focused on those epigenetic modifications which modulate chromatin structure to guarantee that information present on DNA is read correctly and at the most appropriate time in order to meet cellular requirements.
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Epigenetic Regulation of Adult Myogenesis
2018Skeletal muscle regeneration is an efficient stem cell-based repair system that ensures healthy musculature. For this repair system to function continuously throughout life, muscle stem cells must contribute to the process of myofiber repair as well as repopulation of the stem cell niche.
Daniel C L, Robinson +1 more
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Epigenetic regulation and heart failure
Expert Review of Cardiovascular Therapy, 2014Heart failure has become a huge public health problem. The treatment options for heart failure, however, are considerably limited. The significant disparity between the scope of a prominent health problem and the restricted means of therapy propagates heart failure epidemics. Delineating novel mechanisms of heart failure is imperative.
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Epigenetic regulation of inflammation
Seminars in Cell & Developmental Biologyopenaire +2 more sources