Results 101 to 110 of about 88,530 (198)

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Antidepressant treatment is associated with epigenetic alterations of Homer1 promoter in a mouse model of chronic depression

, 2020
Lu Sun, Rikst-Nynke Verkaik-Schakel, Knut Biber, Torsten Plösch, Tsvetan Serchov   +4 more
openalex   +2 more sources

Epicutaneous Immunotherapy Induces Epigenetic Changes In Sensitized Mice [PDF]

, 2014
Lucie Mondoulet, Vincent Dioszeghy, Mélanie Ligouis, Véronique Dhelft, Emilie Puteaux, Camille Plaquet, Christophe Dupont, Pierre Henri Benhamou   +7 more
openalex   +1 more source

Epigenetic Therapy Augments Classic Chemotherapy in Suppressing the Growth of 3D High-Grade Serous Ovarian Cancer Spheroids over an Extended Period of Time [PDF]

, 2021
Michelle Bilbao, Chelsea Katz, SL Kass, Devon Smith, Krystal Hunter, David Warshal, James K. Aikins, Olga Ostrovsky   +7 more
openalex   +1 more source

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Evolving Boolean regulatory networks with epigenetic control [PDF]

, 2013
Larry Bull
openalex   +1 more source

Epigenetic Inheritance: Impact for Biology and Society—recent progress, current questions and future challenges [PDF]

, 2022
Rodrigo G. Arzate‐Mejía, Isabelle M. Mansuy   +1 more
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Epigenetic Factors that Control Pericentric Heterochromatin Organization in Mammals [PDF]

, 2020
Salvatore Fioriniello, Domenico Marano, Francesca Fiorillo, Maurizio D’Esposito, Floriana Della Ragione   +4 more
openalex   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source