Results 101 to 110 of about 458,162 (417)
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
The Effects of Epigenetics on Stress Response [PDF]
, 2016 Despite the vast amount of resources at the disposal of humanity today, the intricacies of human biology are often a mystery. The chemical and biological products of the human genome have been well studied and documented, but many of the chemical and ...
Suddarth, Kevin
core +1 more source
The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]
, 2020 Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core
Current Rheumatology Reports, 2017 Systemic lupus erythematosus is a severe autoimmune/inflammatory condition of unknown pathophysiology. Though genetic predisposition is essential for disease expression, risk alleles in single genes are usually insufficient to confer disease. Epigenetic dysregulation has been suggested as the missing link between genetic risk and the development of ...
openaire +4 more sources
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Magnetic Polymer Models for Epigenetics-Driven Chromosome Folding [PDF]
, 2019 Epigenetics is a driving force of important and ubiquitous phenomena in nature such as cell differentiation or even metamorphosis. Oppositely to its widespread role, understanding the biophysical principles that allow epigenetics to control and rewire gene regulatory networks remains an open challenge.
arxiv +1 more source
The Effects of the Type and Timing of Dietary Folate on Memory, Learning, and Gene Expression in Mice [PDF]
, 2018 Folate has been known as an important vitamin for several decades. It is vital in development and epigenetics and is especially known for its involvement in the prevention of neural tube defects in newborns.
Schreiner, Caleb
core +1 more source
Epigenetics in diagnosis, prognostic assessment and treatment of cancer:An update [PDF]
, 2014 Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and ...
Briasoulis, Evangelos +4 more
core +4 more sources
Will epigenetics ever be a biosocial science? A reply to Chiapperino and Paneni
Epigenetics Communications, 2023 The recent correspondence article by Chiapperino and Paneni in Clinical Epigenetics correctly points to the inability of epigenetics to incorporate fine-grained mapping data of the individual’s surrounding milieu.
Silvio Zaina
doaj +1 more source
Genes to Cells, 2012 Induced pluripotent stem (iPS) cells have provided a rational means of obtaining histo‐compatible tissues for ‘patient‐specific’ regenerative therapies (Hanna et al. 2010; Yamanaka & Blau 2010). Despite the obvious potential of iPS cell‐based therapies, there are certain problems that must be overcome before these therapies can become safe and ...
Prim B. Singh, Maria Manukyan
openaire +3 more sources