Results 91 to 100 of about 150,500 (308)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Global research progress of gut microbiota and epigenetics: bibliometrics and visualized analysis
Frontiers in ImmunologyBackgroundGut microbiota is an important factor affecting host health. With the further study of the mechanism of gut microbiota, significant progress has been made in the study of the link between gut microbiota and epigenetics.
Siyu Tian, Min Chen
doaj +1 more source
bgruening/docker-galaxy-epigenetics: 17.09 release
, 2017 :whale::bar_chart::books: Docker Images for epigenetics data ...
Joachim Wolff, Björn Grüning
core +1 more source
, 2023 DNA Replication - Mechanisms, Epigenetics, and Gene Therapy Applications presents the latest trends of DNA replication research by reviewing the fundamentals of molecular mechanisms of initiation and termination, functional cross-talk and/or association ...
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Preface to nutrition and epigenetics
, 2009 The scope of this book is to focus on this novel, fascinating field pertaining to the role of nutritional factors in affecting epigenetic mechanisms therefore highlighting the vast topic that derives from a better understanding of the function of ...
FRISO, Simonetta, Sang Woon Choi
core +1 more source
The ghost in our genes: legal and ethical implications of epigenetics.
, 2009 Epigenetics is one of the most scientifically important, and legally and ethically significant, cutting-edge subjects of scientific discovery. Epigenetics link environmental and genetic influences on the traits and characteristics of an individual, and ...
Rothstein, Mark A. +2 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Epigenetics—Innovations and Misconceptions
Natural SciencesEpigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in ...
Bernhard Horsthemke
doaj +1 more source