Results 211 to 220 of about 369,301 (351)

Genetic and Epigenetic Changes in Human Epithelial Cells Immortalized by Telomerase [PDF]

, 2000
D. Gregory Farwell, Katherine A. Shera, Jennifer I. Koop, George A. Bonnet, Connie P. Matthews, Gary W. Reuther, Marc D. Coltrera, James K. McDougall, Aloysius J. Klingelhutz   +8 more
openalex   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Long-lasting metabolic impairment in the failing heart: epigenetic memories at play. [PDF]

Epigenetics
Costantino S, Paneni F.
europepmc   +1 more source

Modulation of EGFR Gene Transcription by a Polymorphic Repetitive Sequence – a Link between Genetics and Epigenetics [PDF]

, 2000
Frank Gebhardt, Horst Bürger, Burkhard Brandt   +2 more
openalex   +1 more source

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

Advanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio‐Lopez, Douglas Hazel, Michael Levin   +6 more
wiley   +1 more source

RETRACTED: Sibuh et al. The Emerging Role of Epigenetics in Metabolism and Endocrinology. <i>Biology</i> 2023, <i>12</i>, 256. [PDF]

Biology (Basel)
Sibuh BZ, Quazi S, Panday H, Parashar R, Jha NK, Mathur R, Jha SK, Taneja P, Jha AK.   +8 more
europepmc   +1 more source

Cytosine Methylation Associated With Repeat-Induced Point Mutation Causes Epigenetic Gene Silencing in Neurospora crassa

, 1997
Jeffrey T. Irelan, Eric U. Selker
openalex   +2 more sources

Epigenetics and its role in disease [PDF]

, 2000
Benjamin Tycko, John Ashkenas
openalex   +1 more source

Epigenetics and pharmaco-epigenetics in the primary headaches [PDF]

The Journal of Headache and Pain, 2008
openaire   +3 more sources

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source