Retraction Note to: A novel miRNA identified in GRSF1 complex drives the metastasis via the PIK3R3/AKT/NF-κB and TIMP3/MMP9 pathways in cervical cancer cells. [PDF]
Sun Q+7 more
europepmc +1 more source
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang+10 more
wiley +1 more source
Epigenetics Through Generations and Across Phylogenies: An Interview with Dr. Bluma Lesch. [PDF]
Abu-Shamma R, Marijic Buljubasic A.
europepmc +1 more source
The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang+16 more
wiley +1 more source
Correction: Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3. [PDF]
Cao Y+11 more
europepmc +1 more source
DNA hypermethylation in tumorigenesis: epigenetics joins genetics
Stephen B. Baylin, James G. Herman
openalex +1 more source
Protein-coding genes are epigenetically regulated in Arabidopsis polyploids [PDF]
Hyeon-Se Lee, Z. Jeffrey Chen
openalex +1 more source
Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao+13 more
wiley +1 more source
Interplay between genes and social environment: from epigenetics to precision medicine. [PDF]
Caporali S+4 more
europepmc +1 more source
Epigenetic randomness, complexity and singularity of human iris patterns [PDF]
John Daugman, Cathryn Downing
openalex +1 more source