Results 231 to 240 of about 495,214 (384)

Non-coding RNAs as regulators in epigenetics (Review).

Oncology Report, 2017
Jianwei Wei, Kai Huang, Chao Yang, C. Kang   +3 more
semanticscholar   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Correction: Acetylation modification of AIM2 by KAT2B suppresses the AKT/Wnt/β-catenin signaling pathway activation and inhibits breast cancer progression. [PDF]

Epigenetics Chromatin
Li Y, Wang L, Wanga W, Wangb W, Huang W, Liu S.   +5 more
europepmc   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Editorial: Epigenetics, transcriptomics and epitranscriptomic - deal with old friends or new direction of regulation? [PDF]

Front Plant Sci
Wang J, Kubala S.
europepmc   +1 more source

Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice [PDF]

, 2017
Emily L. Rossi, Sarah M. Dunlap, Laura W. Bowers, Subreen A. Khatib, Steven S. Doerstling, Laura Smith, Nikki A. Ford, Darcy Holley, Powel H. Brown, Marcos R. Estecio, Donna F. Kusewitt, Linda A. deGraffenried, Scott J. Bultman, Stephen D. Hursting   +13 more
openalex   +1 more source

Epigenetics rules [PDF]

Journal of Ocular Biology, Diseases, and Informatics, 2011
Evgenya, Popova, Colin J, Barnstable
openaire   +2 more sources

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Author Correction: SOX2 drives esophageal squamous carcinoma by reprogramming lipid metabolism and histone acetylation landscape. [PDF]

Nat Commun
Wang Z, Dai R, Kang L, Yang H, Chen Z, He J, Shu L, Zhong Y, Zhang Y, Hua Z, Huang Y, Jiang Y, Li J, Xu L, Lan F, Lin SH, Wong J.   +16 more
europepmc   +1 more source