Results 281 to 290 of about 495,214 (384)

Environmental epigenomics and the human imprintome. [PDF]

Environ Epigenet
Jirtle RL.
europepmc   +1 more source

RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation

, 2018
Rahyza Inácio Freire de Assis, Małgorzata Wiench, Karina Gonzáles Silvério, Rodrigo A. da Silva, Géorgia da Silva Feltran, Enílson Antônio Sallum, Márcio Zaffalon Casati, Francisco Humberto Nociti, Denise Carleto Andia   +8 more
openalex   +2 more sources

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

CIRCpedia v3: an interactive database for circular RNA characterization and functional exploration. [PDF]

Nucleic Acids Res
Zhai SN, Zhang YY, Chen MH, Fu ZC, Chen LL, Ma XK, Yang L.   +6 more
europepmc   +1 more source

Genome-Wide DNA Methylation Analysis Reveals Epigenetic Pattern of SH2B1 in Chinese Monozygotic Twins Discordant for Autism Spectrum Disorder

, 2019
Shuang Liang, Zhenzhi Li, Yihan Wang, Xiaodan Li, Xiaolei Yang, Xiaolei Zhan, Yan Huang, Zhaomin Gao, Min Zhang, Caihong Sun, Yan Zhang, Lijie Wu   +11 more
openalex   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers. [PDF]

Nucleic Acids Res
Lu Z, Sun H, Fu B, Ao Y, Wang J, Chen K, Luo Y, Li L, Qiu Z, Zhao J, Sun Y, Tan Z, Liu Q, Ren Y, Guo Z, Chen X, He Y, Zhao Y, Chen Y, Li M, Peng X, Huang B, Zhu S, Huang L, Miao Z.   +24 more
europepmc   +1 more source

Alterations in the glycome after HDAC inhibition impact oncogenic potential in epigenetically plastic SW13 cells [PDF]

, 2019
McKale R. Montgomery, Elizabeth Hull
openalex   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Correction: Decoding the PTTG family's contribution to LUAD pathogenesis: a comprehensive study on expression, epigenetics, and therapeutic interventions. [PDF]

Hereditas
Di J, Tian L, Yan F, Zhe Z, Lin C, Jingyu L.   +5 more
europepmc   +1 more source