Results 281 to 290 of about 189,865 (294)
Some of the next articles are maybe not open access.
Pancreatology, 2007
'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed.
openaire +2 more sources
'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed.
openaire +2 more sources
WIREs Systems Biology and Medicine, 2016
Why do we grow up to have the traits we do? Most 20th century scientists answered this question by referring only to our genes and our environments. But recent discoveries in the emerging field of behavioral epigenetics have revealed factors at the interface between genes and environments that also play crucial roles in development.
openaire +2 more sources
Why do we grow up to have the traits we do? Most 20th century scientists answered this question by referring only to our genes and our environments. But recent discoveries in the emerging field of behavioral epigenetics have revealed factors at the interface between genes and environments that also play crucial roles in development.
openaire +2 more sources
Pharmacopsychiatry, 2012
Investigations on gene variants as milestones in the development of schizophrenia have not fulfilled the enormous, initial expectations. Neither candidate gene approaches trying to associate single genes with the disorder, nor genome-wide association studies (GWAS), that have been welcomed more recently with great enthusiasm, could end the general ...
openaire +2 more sources
Investigations on gene variants as milestones in the development of schizophrenia have not fulfilled the enormous, initial expectations. Neither candidate gene approaches trying to associate single genes with the disorder, nor genome-wide association studies (GWAS), that have been welcomed more recently with great enthusiasm, could end the general ...
openaire +2 more sources
Journal of the European Academy of Dermatology and Venereology, 2011
AbstractIncreasing evidence indicates that epigenetic mechanisms are involved in the pathogenesis of autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The pathogenesis of the organ‐specific autoimmune disease psoriasis, however, remains poorly understood.
P, Zhang, Y, Su, Q, Lu
openaire +2 more sources
AbstractIncreasing evidence indicates that epigenetic mechanisms are involved in the pathogenesis of autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The pathogenesis of the organ‐specific autoimmune disease psoriasis, however, remains poorly understood.
P, Zhang, Y, Su, Q, Lu
openaire +2 more sources
2012
During newt lens regeneration a unique transdifferentiation event occurs. In this process, dorsal iris pigmented epithelial cells transdifferentiate into lens cells. This system should provide a new insight into cellular plasticity in basic and applied research.
Nobuyasu, Maki, Hironobu, Kimura
openaire +2 more sources
During newt lens regeneration a unique transdifferentiation event occurs. In this process, dorsal iris pigmented epithelial cells transdifferentiate into lens cells. This system should provide a new insight into cellular plasticity in basic and applied research.
Nobuyasu, Maki, Hironobu, Kimura
openaire +2 more sources
Annals of the New York Academy of Sciences, 2011
Accumulating epidemiological, clinical, and experimental evidence supports the conclusion of a critical role of epigenetic factors in immune programming. This understanding provides the basis for elucidating how the intricate interactions of the genome, epigenome, and transcriptome shape immune responses and maintain immune tolerance to self‐antigens ...
openaire +2 more sources
Accumulating epidemiological, clinical, and experimental evidence supports the conclusion of a critical role of epigenetic factors in immune programming. This understanding provides the basis for elucidating how the intricate interactions of the genome, epigenome, and transcriptome shape immune responses and maintain immune tolerance to self‐antigens ...
openaire +2 more sources
Perspectives in Biology and Medicine, 2014
Early studies of the developing embryo raised the question of how a fertilized egg could give rise to a complex multicellular organism containing many different kinds of cells. The term epigenetics originally referred to the study of these processes.
openaire +2 more sources
Early studies of the developing embryo raised the question of how a fertilized egg could give rise to a complex multicellular organism containing many different kinds of cells. The term epigenetics originally referred to the study of these processes.
openaire +2 more sources
2014
Among different mechanisms that could lead to interindividual differences in obesity susceptibility, epigenetics has emerged, in the last years, as a potentially very important contributor. The role of epigenetics in obesity may be considered by different points of view.
FRISO, Simonetta, Sang Woon Choi
openaire +2 more sources
Among different mechanisms that could lead to interindividual differences in obesity susceptibility, epigenetics has emerged, in the last years, as a potentially very important contributor. The role of epigenetics in obesity may be considered by different points of view.
FRISO, Simonetta, Sang Woon Choi
openaire +2 more sources
2014
Traditional treatments for cancer include chemotherapy, radiation therapy, and surgery. Recently, epigenetic inhibitors have been found to be very effective in cancer treatment. Epigenetic changes such as DNA methylation, histone deacetylation, and microRNA (miRNA) expression are capable of silencing the expression of tumor suppressor genes and ...
Mukesh, Verma, Hirendra Nath, Banerjee
openaire +2 more sources
Traditional treatments for cancer include chemotherapy, radiation therapy, and surgery. Recently, epigenetic inhibitors have been found to be very effective in cancer treatment. Epigenetic changes such as DNA methylation, histone deacetylation, and microRNA (miRNA) expression are capable of silencing the expression of tumor suppressor genes and ...
Mukesh, Verma, Hirendra Nath, Banerjee
openaire +2 more sources