Results 161 to 170 of about 89,797 (267)
Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino +15 more
wiley +1 more source
Interactions between nutrition and the epigenome: how can it be harnessed for public health? [PDF]
Anastasopoulou M +3 more
europepmc +1 more source
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu +8 more
wiley +1 more source
Spatial multi-omics integration by cross-modal graph contrastive learning. [PDF]
Gui Y, Xu Y, Li C.
europepmc +1 more source
Recovery From Anorexia Nervosa: A Concept Analysis
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley +1 more source
Epigenetic Editing in Neurological and Neuropsychiatric Disorders: Pioneering Next-Gen Therapeutics for Precision Gene Control. [PDF]
Marei HE.
europepmc +1 more source
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor +6 more
wiley +1 more source
Epigenetic regulation of mycorrhizal symbioses: from plastic responses to transgenerational legacies
Summary Mycorrhizal symbioses represent one of the most widespread and ecologically significant plant–microbe interactions, shaping plant nutrition, stress resilience, and ecosystem functioning. Beyond their role in nutrient exchange and systemic defense, growing evidence suggests that these symbioses also influence plant plasticity within and across ...
Gerson Beltrán‐Torres +9 more
wiley +1 more source
Recombination suppression in plant adaptation and speciation
Summary Recombination suppression is increasingly recognized as an important facilitator of genomic divergence and speciation, especially under ongoing gene flow. In plants, however, the broader evolutionary consequences and the mechanisms by which recombination suppression arises and spreads are still incompletely understood, reflecting the inherent ...
Xu Zhang +4 more
wiley +1 more source
Advances and challenges of precision epigenetic therapy in treating genomic imprinting diseases. [PDF]
Lv Y, Li M, Ji C.
europepmc +1 more source

