Results 211 to 220 of about 59,868 (318)

Unstable anthocyanin pigmentation in Streptocarpus sect. Saintpaulia (African violet) is due to transcriptional selectivity of a single MYB gene

open access: yesNew Phytologist, Volume 247, Issue 3, Page 1426-1444, August 2025.
Summary Saintpaulia (African violet) pigmentation is notoriously unstable and sometimes forms white stripes, particularly following passage through tissue culture. White‐striped petals were thought to be due to periclinal chimeras, but we confirmed that white stripes result from epigenetic regulation rather than periclinal chimeras based on the flower ...
Daichi Kurata   +5 more
wiley   +1 more source

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 282-307, July/August 2025.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari   +7 more
wiley   +1 more source

News about old histones: A role for histone age in controlling the epigenome [PDF]

open access: bronze, 2012
Fred van Leeuwen   +4 more
openalex   +1 more source

UTAP2: an enhanced user-friendly transcriptome and epigenome analysis pipeline. [PDF]

open access: yesBMC Bioinformatics
Lindner J   +6 more
europepmc   +1 more source

Antitumor efficacy of intermittent low‐dose erlotinib plus sulindac via MHC upregulation and remodeling of the immune cell niche

open access: yesInternational Journal of Cancer, Volume 157, Issue 2, Page 355-370, 15 July 2025.
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi   +17 more
wiley   +1 more source

Biological Mechanisms for Allen's Rule: DNA Methylation as Mediator of the Association Between In Utero Exposure to Environmental Heat and Tibial Growth in Childhood

open access: yesAmerican Journal of Human Biology, Volume 37, Issue 7, July 2025.
Our study contributes to a frontier stage in scientific studies on the precise epigenetic mechanisms regulating phenotypic plasticity in humans in response to heat stress for complex traits like linear growth. We present evidence of an indirect effect (through DNA methylation) of heat exposure in utero on later childhood differences through one ...
Bilinda Straight   +7 more
wiley   +1 more source

Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study [PDF]

open access: hybrid, 2013
Bertha Hidalgo   +9 more
openalex   +1 more source

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