Results 221 to 230 of about 93,647 (322)
Dissecting the epigenome dynamics in human immune cells upon viral and chemical exposure by multimodal single-cell profiling [PDF]
Irem B. Gündüz +25 more
openalex +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Correction: Precision scalpels for the epigenome: next-gen editing tools in targeted therapies. [PDF]
Zhang R +7 more
europepmc +1 more source
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source
From Methylomes to CRISPR Epigenetic Editing: New Paths in Antibiotic Resistance. [PDF]
Nass NM, Zaher KA.
europepmc +1 more source
"New techniques" of modification of the genomes and epigenomes (NTMGE)
Yves Bertheau
openalex +1 more source
ChromNet enables accurate cross‐cell‐type prediction of chromatin architecture from DNA and epigenetic profiles alone, capturing both conserved and cell‐type‐specific (including disease‐associated) structural features. Its noise‐perturbed multi‐task learning design enhances generalization, enabling precise reconstruction of 3D genome organization even ...
Bin Wang +5 more
wiley +1 more source
Epigenetic regulation of brain development, plasticity, and response to early-life stress. [PDF]
Peña CJ.
europepmc +1 more source

