Results 271 to 280 of about 93,647 (322)

Dad's Diet Shapes the Future: How Paternal Nutrition Impacts Placental Development and Childhood Metabolic Health. [PDF]

Mol Nutr Food Res
Skerrett-Byrne DA, Pepin AS, Laurent K, Beckers J, Schneider R, Hrabě de Angelis M, Teperino R.   +6 more
europepmc   +1 more source

Multiplex Epigenome Editing of Dorsal Root Ganglion Neuron Receptors Abolishes Redundant Interleukin 6, Tumor Necrosis Factor Alpha, and Interleukin 1β Signaling by the Degenerative Intervertebral Disc

, 2019
Joshua D. Stover, Niloofar Farhang, Brandon D. Lawrence, Robby D. Bowles   +3 more
openalex   +2 more sources

Genomic Perspective on Heterogeneity of Organs and Body Aging

Aging Cell, Volume 25, Issue 1, January 2026.
Organ‐specific and whole‐body intrinsic aging metrics reveal heterogeneous organ aging, which potentially can arise from the interplay between static germline variation, somatic mutations, epigenetic drift, transposable elements, and mitochondrial DNA changes, highlighting genomic pathways for precision, organ‐targeted aging interventions.
Shabnam Salimi, Daniel Raftery, Luigi Ferrucci   +2 more
wiley   +1 more source

Pituitary Neuroendocrine Tumor or Pituitary Adenoma? Let's Ask the Epigenome! [PDF]

Endocr Pathol
Dottermusch M.
europepmc   +1 more source

Integration of omics data in the diagnosis and therapy of glioblastoma

Brain Pathology, Volume 36, Issue 1, January 2026.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller, Melanie Schoof, Keith L. Ligon, Ulrich Schüller   +3 more
wiley   +1 more source

Childhood obesity and DNA methylation in an epigenome-wide association study: findings from the Hokkaido Birth Cohort. [PDF]

Clin Epigenetics
Iwata H, Miyashita C, Yamaguchi T, Ikeda A, Miura R, Minatoya M, Tamura N, Ait Bamai Y, Itoh S, Yamazaki K, Ketema RM, Itoh M, Tojo M, Yamamoto R, Makino K, Kishi R.   +15 more
europepmc   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, Volume 183, Issue 1, Page 24-39, January 2026.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

Tauroursodeoxycholic acid as a beneficial modulator for developmentally programed chromatin structure around specific genes

Frontiers in Endocrinology
Hiroaki Itoh, Tomoko Aoyama, Yukiko Kohmura-Kobayashi, Naoaki Tamura, Takahiro Nemoto   +4 more
doaj   +1 more source

Environmental epigenomics and the human imprintome. [PDF]

Environ Epigenet
Jirtle RL.
europepmc   +1 more source

A CpG Epigenetic Switch Reverts PFAS ToxicityAn In Vitro Study. [PDF]

Environ Health (Wash)
Sands M, Wen Y, Sachdeva A, Irudayaraj J.   +3 more
europepmc   +1 more source