Results 191 to 200 of about 55,460 (328)

Brain DNA Methylation Atlas of AppNL‐G‐F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline‐Induced Resilience

Aging Cell, EarlyView.
Brain DNA methylation drives abnormal gene expression in AppNL‐G‐F mice. Perinatal choline supplementation may promote resilience to synaptic dysfunction through modulation of DNA methylation. ABSTRACT Alzheimer's disease (AD) is the most common type of dementia.
Andre Krunic, Thomas A. Bellio, Benjamin Z. Cohen, Adam Labadorf, Thor D. Stein, Honghuang Lin, Tiffany J. Mellott, Jan K. Blusztajn   +7 more
wiley   +1 more source

Epigenomics: maternal high‐fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates

, 2010
Melissa Suter, Philip Bocock, Lori Showalter, Min Hu, Cynthia Shope, Robert A. McKnight, Kevin L. Grove, Robert H. Lane, Kjersti Aagaard‐Tillery   +8 more
openalex   +2 more sources

Toll-like receptor 2 deficiency induces epigenomic, transcriptomic and microbiomic changes in the colonic mucosa of mice. [PDF]

, 2011
Richárd Kellermayer, Alfred Balasa, Alan W. Harris, Tiffany D. Schaible, Scot E. Dowd, Nina Tatevian, Réka Szigeti, William Kojo Smith   +7 more
openalex   +1 more source

Liver molecular networks associated with drinking behavior in nonhuman primates

Alcohol, Clinical and Experimental Research, EarlyView.
We identified hepatic molecular networks that differed between light drinkers (LD) and very heavy drinkers (VHD) before they were exposed to alcohol, as well as epigenetic differences between LD and VHD in response to the same amount of alcohol.
Laura A. Cox, James B. Daunais, Timothy D. Howard, Ge Li, Sobha Puppala, Jeannie Chan, Zeeshan Hamid, Samer Gawrieh, Sun Mi Lee, Betsy Ferguson, Kathleen A. Grant, Michael Olivier   +11 more
wiley   +1 more source

Pituitary Neuroendocrine Tumor or Pituitary Adenoma? Let's Ask the Epigenome! [PDF]

Endocr Pathol
Dottermusch M.
europepmc   +1 more source

Surveying the epigenomic landscape, one base at a time [PDF]

, 2012
Gabriel E. Zentner, Steven Henikoff
openalex   +1 more source

Understanding the Variability of Peanut‐Oral Immunotherapy Responses by Multi‐Omics Profiling of Immune Cells

Allergy, EarlyView.
This study analyzes molecular drivers of OIT responsiveness. Multi‐omics profiling of peanut‐stimulated PBMCs in a controlled peanut‐OIT trial identifies immune, transcriptomic, and epigenetic changes distinguishing complete responders from incomplete responders. Key findings highlight gastrointestinal immune mechanisms, including extracellular exosome
Aleix Arnau‐Soler, Sarah E. Ashley, Ahla Ghauri, Alexander C. S. N. Jeanrenaud, Ingo Marenholz, Katharina Blumchen, Penelope Cibin, Alisa Iakupova, Norbert Hubner, Kirsten Beyer, Young‐Ae Lee   +10 more
wiley   +1 more source

Author Correction: Regulatory genomic circuitry of human disease loci by integrative epigenomics. [PDF]

Nature
Boix CA, James BT, Park YP, Meuleman W, Kellis M.   +4 more
europepmc   +1 more source

Maps for Changing Landscapes: Viewing Epigenomic Signatures through Differentiation [PDF]

, 2012
Michael Bulger
openalex   +1 more source

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, on behalf of the Southern Italy Network on Severe Asthma Therapy, Rossella Intravaia, Morena Porto, Pietro Impellizzeri, Maria Provvidenza Pistorio, Fabio Vignera, Andrea Alessia Nardo, Concetta Giannì, Silvano Dragonieri, Flogerta Sana, Valeria Pezzuto, Santina Ferulli, Massimo Triggiani, Roberta Parente, Pasquale Tondo, Piera Soccio, Donato Lacedonia, Luigi Ciampo, Antonio Franzese, Valeria Longobardi   +38 more
wiley   +1 more source