Results 191 to 200 of about 33,317 (303)

The evolving role of OMICS in gastrointestinal tumor biology and clinical practice. [PDF]

Mol Cancer
Li Q, Zhang J, Chen J, Zhang Q, Liu R, Zhu J, Qing Y, Wei X, Sheng J.   +8 more
europepmc   +1 more source

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source

Learning a pairwise epigenomic and transcription factor binding association score across the human genome. [PDF]

Bioinformatics
Kwon SB, Ernst J.
europepmc   +1 more source

Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu, Jiaying Ni, Qian Dou, Hang Su, Ziyi Zhang, Xiaojing Ma, Qing Dai, Jian Zhou   +7 more
wiley   +1 more source

Impact of OMICS Technologies in Our Understanding of the Pathogenesis of Peri-Implantitis. [PDF]

Clin Exp Dent Res
Asa'ad F, Hasuike A, Yoshida K, Lira-Junior R, Chaurasia A, Giraldo-Osorno PM, Garaicoa-Pazmino C.   +6 more
europepmc   +1 more source

Minimal Residual Disease as a Biological Trait: Rethinking Disease Persistence in Hematologic Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Minimal residual disease (MRD) has emerged as a central biomarker in hematologic malignancies, enabling highly sensitive detection of tumor persistence beyond conventional morphologic assessment and serving as an increasingly important surrogate endpoint in clinical trials.
Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Mamdouh Skafi, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +14 more
wiley   +1 more source

Longevity Aesthetics: A Conceptual Framework for Integrating Pro-Aging Medicine Into Surgical and Nonsurgical Practice. [PDF]

Aesthet Surg J Open Forum
Haykal D, Nahai F.
europepmc   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

S-adenosylmethionine as an epigenetic treatment of depression in adults with childhood trauma. [PDF]

Epigenomics
Alkema A, Schalkwijk W, Bohte E, Draisma L, Hoppe A, Koch C, Refuge V, Romberg B, Luykx JJ, Jans JJM, Cahn W, Regeer E, Boks MPM.   +12 more
europepmc   +1 more source

Immunophenotypic assessment of pure embryonal carcinoma and yolk sac tumour suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche

Histopathology, EarlyView.
Immunohistochemical analysis of transcription factors in GCNIS associated with pure EC and YST suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche. In these tumors, reprogramming may occur immediately upon invasion of the stroma or within seminiferous tubules but outside the spermatogonial niche (i.e., in intratubular ...
Daisy Maharjan, Květoslava Michalová, Joao Lobo, Jennifer Gordetsky, Fiona MacLean, Ankur R Sangoi, Daniel Berney, Chia‐Sui Kao, Costantino Ricci, Adeboye O Osunkoya, Maria Rosaria Raspollini, Geert JLH van Leenders, Muhammad T Idrees, Lee Ann Baldridge, Thomas M Ulbright, Andres M Acosta   +15 more
wiley   +1 more source