Results 281 to 290 of about 43,487 (351)

Artificial intelligence and anti-cancer drugs' response. [PDF]

Acta Pharm Sin B
Long X, Sun K, Lai S, Liu Y, Su J, Chen W, Liu R, He X, Zhao S, Huang K.   +9 more
europepmc   +1 more source

Perspectives on integrating artificial intelligence and single‐cell omics for cellular plasticity research

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cellular plasticity enables cells to dynamically adapt to environmental changes by altering their phenotype. This plasticity plays a crucial role in tissue repair and regeneration and contributes to pathological processes such as cancer metastasis.
Ahmed Ghobashi, Qin Ma
wiley   +1 more source

Methylation aberrations and genomic instability synergistically drive the evolution of intrahepatic cholangiocarcinoma. [PDF]

Epigenomics
Li G, Bai Y, Tao F, Hu T, Wang T, Zeng Y, Sun D.   +6 more
europepmc   +1 more source

Cell lineage tracing: Methods, applications, and challenges

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cell lineage tracing is a crucial technique for understanding cell fate and lineage relationships, with wide applications in developmental biology, tissue regeneration, and disease progression studies. Over the years, experimental cell lineage tracing methods have advanced from early labeling techniques to modern genetic tools such as CRISPR ...
Shanjun Mao, Chenyang Zhang, Runjiu Chen, Shan Tang, Xiaodan Fan, Jie Hu   +5 more
wiley   +1 more source

Mechanisms and technologies in cancer epigenetics. [PDF]

Front Oncol
Sherif ZA, Ogunwobi OO, Ressom HW.
europepmc   +1 more source

Revolutionizing multi‐omics analysis with artificial intelligence and data processing

Quantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Our understanding of intricate biological systems has been completely transformed by the development of multi‐omics approaches, which entail the simultaneous study of several different molecular data types. However, there are many obstacles to overcome when analyzing multi‐omics data, including the requirement for sophisticated data processing
Ali Yetgin
wiley   +1 more source

Vaginal microbiome composition in women with HIV undergoing treatment of cervical transformation zone in a screen and treat program in Zambia. [PDF]

AIDS
Pinder LF, Bertrand P, Fertitta V, Cahais V, Mwanahamuntu M, Nyambe N, Chisele S, Shibemba AL, McKay-Chopin S, Cuenin C, Lucas E, Korenjak M, Muwonge R, Ghantous A, Herceg Z, Parham GP, Zavadil J, Basu P, Gheit T.   +18 more
europepmc   +1 more source

An effective encoding of human medical conditions in disease space provides a versatile framework for deciphering disease associations

Quantitative Biology, Volume 13, Issue 3, September 2025.
Abstract It is challenging to identify comorbidity patterns and mechanistically investigate disease associations based on health‐related data that are often sparse, large‐scale, and multimodal. Adopting a systems biology approach, embedding‐based algorithms provide a new perspective to examine diseases under a unified framework by mapping diseases into
Tianxin Xu, Yu Li, Xin Gao, Andrey Rzhetsky, Gengjie Jia   +4 more
wiley   +1 more source

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

BioEssays, Volume 47, Issue 8, August 2025.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source