Results 281 to 290 of about 55,460 (328)

Dynamic microRNA Responses Contribute to Phenotypic Plasticity and Stress Memory in Invasive Species

Molecular Ecology, EarlyView.
Zhenyong Du
wiley   +1 more source

Single‐cell mitochondrial lineage tracing: Opportunities and challenges

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Lineage tracing using endogenous mitochondrial DNA (mtDNA) variants holds great promise for reconstructing the lineage histories of individual cells, with broad applications in oncology, developmental biology, and regenerative medicine.
Siqi Li, Kun Wang, Xin Wang, Zheng Hu
wiley   +1 more source

Novel approaches and applications in identifying DNA methylation markers of cardio-kidney-metabolic disease. [PDF]

Epigenomics
Liu C, Young A, Abi N, Chen J, Fernandes Gyorfy M, Li Y, Sun S, Zhou JJ, Sun YV.   +8 more
europepmc   +1 more source

Single‐cell multi‐omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying CRC‐unique features

International Journal of Cancer, Volume 157, Issue 12, Page 2619-2634, 15 December 2025.
What's New? Patient‐derived organoids provide a promising platform for modeling colorectal cancer. The authors demonstrated that organoids derived from normal colorectal tissue recapitulate the cellular composition and differentiation trajectory of colorectal crypts.
Zhijun Yu, Merel Derksen, Brigit M. te Pas, Sabrina Ladstätter, Rene Overmeer, Peter Brazda, Marc van de Wetering, Farzin Pourfarzad, Robert G. J. Vries, Wout Megchelenbrink, Christoph Bock, Lucia Altucci, Hendrik G. Stunnenberg   +12 more
wiley   +1 more source

Mediators of maternal intergenerational epigenetic inheritance in mammals. [PDF]

Epigenomics
Belton C, Kelsey G.
europepmc   +1 more source

Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell‐Based Regeneration

JOR SPINE, Volume 8, Issue 4, December 2025.
Intervertebral disc degeneration (IDD) is a multifactorial condition underpinned by complex molecular mechanisms. This review highlights advances in RNA sequencing and multi‐omics approaches that have elucidated gene regulatory networks, cellular heterogeneity, and progenitor cell dynamics in the nucleus pulposus.
Anja Stirnimann, Leon Schlagenhof, Benjamin Gantenbein, Fabian Ille   +3 more
wiley   +1 more source

Author Correction: Inferring DNA methylation in non-skeletal tissues of ancient specimens. [PDF]

Nat Ecol Evol
Mathov Y, Nissim-Rafinia M, Leibson C, Galun N, Marques-Bonet T, Kandel A, Liebergall M, Meshorer E, Carmel L.   +8 more
europepmc   +1 more source

Perspectives on integrating artificial intelligence and single‐cell omics for cellular plasticity research

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cellular plasticity enables cells to dynamically adapt to environmental changes by altering their phenotype. This plasticity plays a crucial role in tissue repair and regeneration and contributes to pathological processes such as cancer metastasis.
Ahmed Ghobashi, Qin Ma
wiley   +1 more source

DNA methylation associations with cognitive function in early-stage hormone receptor-positive breast cancer patients. [PDF]

Epigenomics
Liu S, Liu D, Bender CM, Erickson KI, Sereika SM, Shaffer JR, Weeks DE, Conley YP.   +7 more
europepmc   +1 more source