Results 291 to 300 of about 55,460 (328)

Cell lineage tracing: Methods, applications, and challenges

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cell lineage tracing is a crucial technique for understanding cell fate and lineage relationships, with wide applications in developmental biology, tissue regeneration, and disease progression studies. Over the years, experimental cell lineage tracing methods have advanced from early labeling techniques to modern genetic tools such as CRISPR ...
Shanjun Mao, Chenyang Zhang, Runjiu Chen, Shan Tang, Xiaodan Fan, Jie Hu   +5 more
wiley   +1 more source

MicroRNAs‐mediated heat stress regulations in plants: Mechanisms and targets

The Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Heat stress, exacerbated by global warming, can cause significant challenges to agriculture, adversely impacting plant growth, reproduction, and yield. This review examines the crucial role of microRNAs (miRNAs) in mediating plant responses to heat stress across various key crops, including Arabidopsis (Arabidopsis thaliana), rice (Oryza ...
Muhammad Farooq, Hina Tanveer, Hafiz Mamoon Rehman, Rabia Areej Cheema, Sehar Nawaz, Aneesa Ijaz, Muhammad Arif, Hon‐Ming Lam   +7 more
wiley   +1 more source

Science of omics: a molecular space odyssey

Experimental Physiology, EarlyView.
Salomé Coppens, Christophe Hirtz, Margaux Vignon, Damian M. Bailey   +3 more
wiley   +1 more source

Ultrasound Control of Gene Expression in Human iPSCs via Heat Shock Promoters

Biotechnology and Bioengineering, Volume 122, Issue 11, Page 3216-3228, November 2025.
ABSTRACT Inducible systems are crucial tools in biomedical research, offering researchers spatiotemporal control at the cellular level. A promising development in this field is the use of focused ultrasound for controlling gene expression using heat shock promoters (HSPs).
Alessandro R. Howells, Kama Bell, Hyeonu Heo, Tahir Haideri, Yun Jing, Xiaojun Lance Lian   +5 more
wiley   +1 more source

POCALI: Prediction and Insight on CAncer LncRNAs by Integrating Multi-Omics Data with Machine Learning. [PDF]

Small Methods
Rao Z, Wu C, Liao Y, Ye C, Huang S, Zhao D.   +5 more
europepmc   +1 more source

Clinical application of single‐cell RNA sequencing in disease and therapy

Clinical and Translational Medicine, Volume 15, Issue 11, November 2025.
This review provides a comprehensive overview of the application of scRNA‐seq in revisiting the somatic cell evolutions in human diseases, as well as in biomarker discovery and drug development. Abstract Background The emergence of single‐cell RNA sequencing (scRNA‐seq) technology has revolutionized our capacity to study cell functions in complex ...
Aisha Shigna Nadukkandy, Sowmiya Kalaiselvan, Lin Lin, Yonglun Luo   +3 more
wiley   +1 more source

Microbiome as a predictive biomarker in locally advanced rectal cancer. [PDF]

Microbiome Res Rep
Mulet Margalef N, Martín Abad B, Martínez-Balibrea E, Manzano Mozo JL, Borgognone A, Obón-Santacana M.   +5 more
europepmc   +1 more source

Exploring Organ‐Specific Extracellular Vesicles in Metabolic Improvements Following Bariatric Surgery in Youth With Obesity

Obesity, Volume 33, Issue 11, Page 2181-2194, November 2025.
ABSTRACT Objective Vertical sleeve gastrectomy (VSG) promotes significant metabolic improvements, though the underlying molecular mechanisms are not fully understood. Emerging evidence suggests that small extracellular vesicles (sEVs) contribute to metabolic improvements post VSG, such as improved fatty liver disease or adipose tissue function; however,
Ahlee Kim, Tsuyoshi Okura, Kwangmin Choi, Rupinder Gill, Vishnupriya J. Borra, Kazutoshi Murakami, Andrew Poulos, Xiang Zhang, Todd Jenkins, Amy Sanghavi Shah, Michael Helmrath, Takahisa Nakamura   +11 more
wiley   +1 more source

Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following Very Low-Calorie Ketogenic Diet (VLCKD): A New Perspective to Reverse Biological Age. [PDF]

Nutrients
Izquierdo AG, Lorenzo PM, Costa-Fraga N, Primo-Martin D, Rodriguez-Carnero G, Nicoletti CF, Martínez JA, Casanueva FF, de Luis D, Diaz-Lagares A, Crujeiras AB.   +10 more
europepmc   +1 more source