Results 291 to 300 of about 52,554 (369)

Renato Dulbecco: genes, cancer and epigenomics

, 2012
Ileana Zucchi
openalex   +2 more sources

Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancer. [PDF]

Oncogene
Taira A, Aavikko M, Katainen R, Kaasinen E, Välimäki N, Ravantti J, Ristimäki A, Seppälä TT, Renkonen-Sinisalo L, Lepistö A, Tahkola K, Mattila A, Koskensalo S, Mecklin JP, Böhm J, Bramsen JB, Andersen CL, Palin K, Rajamäki K, Aaltonen LA, iCAN.   +20 more
europepmc   +1 more source

Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition

Immunology, Volume 175, Issue 3, Page 300-322, July 2025.
Mevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Tsz Kin Suen, Burcu Al, Thomas Ulas, Nico Reusch, Harsh Bahrar, Siroon Bekkering, Jaydeep Bhat, Dieter Kabelitz, Joachim L. Schultze, Frank L. van de Veerdonk, Jeanine Roeters van Lennep, Niels P. Riksen, Leo A. B. Joosten, Mihai G. Netea, Katarzyna Placek   +14 more
wiley   +1 more source

Epigenetics in persons living with HIV: trauma, coping, and <i>FKBP5</i> and <i>SLC6A4</i> methylation. [PDF]

Epigenomics
Tomlinson CJ, Ryniker L, Cook HM, Schwartz RM, Non AL.   +4 more
europepmc   +1 more source

Obesity‐Induced Metabolic Priming Exacerbates SARS‐CoV‐2 Inflammation

Immunology, Volume 175, Issue 3, Page 323-338, July 2025.
Monocytes primed under obesogenic conditions, such as increased FFA levels (i.e., palmitate) exhibit exacerbated gene expression of inflammatory cytokines. The increased proinflammatory response of palmitate‐primed and SARS‐CoV‐2‐infected monocytes is not dependent on glycolytic metabolism but instead on the entry of FFAs into the mitochondria ...
Gustavo Gastão Davanzo, Bianca Gazieri Castelucci, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Larissa Menezes dos Reis, Isabella Bonilha de Oliveira, José Luís Fachi, João Victor Virgilio‐da‐Silva, Marcelo Rodrigues Berçot, Mariane Font Fernandes, Sarah de Oliveira, Nathalia Vitoria Pereira Araujo, Guilherme Ribeiro, Gisele de Castro, Webster Leonardo Guimarães Costa, Adriana Leandra Santoro, Gabriela Flavia Rodrigues‐Luiz, Helison Rafael P. do Carmo, Ikaro Breder, Marcelo A. Mori, Alessandro S. Farias, Daniel Martins‐de‐Souza, Joseph W. Guarnieri, Douglas C. Wallace, Marco Aurélio Ramirez Vinolo, José Luiz Proença‐Módena, Afshin Beheshti, Andrei C. Sposito, Pedro M. Moraes‐Vieira   +28 more
wiley   +1 more source

Plant MIR2911 in honeysuckle is effective against SARS-CoV-2 variant. [PDF]

Virus Res
Shen CH, Tsai HP, Chou CC, Yeh CS, Yen TH, Huang WL, Wang M, Chan MWY.   +7 more
europepmc   +1 more source

Science of omics: a molecular space odyssey

Experimental Physiology, EarlyView.
Salomé Coppens, Christophe Hirtz, Margaux Vignon, Damian M. Bailey   +3 more
wiley   +1 more source

Dad's legacy: Epigenetic reprogramming and paternal inflammatory memory in offspring health

Journal of Internal Medicine, Volume 298, Issue 1, Page 16-30, July 2025.
Abstract Over the past decade, numerous reports have highlighted intergenerational and even transgenerational epigenetic effects resulting from parental exposure to diets, toxins, and stress. In many cases, these parentally induced phenotypes do not seem to confer an obvious benefit, making it challenging to understand the evolutionary drivers behind ...
Shamila D. Alipoor, Parisa Norouzitallab, Anita Öst, Maria Lerm   +3 more
wiley   +1 more source

Generic and queryable data integration schema for transcriptomics and epigenomics studies. [PDF]

Comput Struct Biotechnol J
Tirlet Y, Boudet M, Becker E, Legeai F, Dameron O.   +4 more
europepmc   +1 more source

Accumulation of Epigenetic Noise in the Aging Corneal Epithelium and Its Possible Mechanism

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
We found an accumulation of epigenetic noise in the aging corneal epithelium, manifested by increases and decreases in DNA methylation levels. Our findings suggest that these changes occur due to reduced activity of TET enzymes. We assume that the age‐related changes in DNA methylation patterns and the activity of TET enzymes reflect the epigenetic ...
Galina Dvoriantchikova, Michelle Fleishaker, Dmitry Ivanov   +2 more
wiley   +1 more source