Results 301 to 310 of about 43,487 (351)
Integrating Artificial Intelligence in Next-Generation Sequencing: Advances, Challenges, and Future Directions. [PDF]
Curr Issues Mol BiolAthanasopoulou K +3 more
europepmc +1 more source
The Epigenomics of Cancer [PDF]
Cell, 2007 Aberrant gene function and altered patterns of gene expression are key features of cancer. Growing evidence shows that acquired epigenetic abnormalities participate with genetic alterations to cause this dysregulation. Here, we review recent advances in understanding how epigenetic alterations participate in the earliest stages of neoplasia, including ...
Peter A Jones
exaly +5 more sources
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
Nature, 2021 Alexander Kleger +2 more
exaly +2 more sources
Regulatory genomic circuitry of human disease loci by integrative epigenomics
Nature, 2021 Annotating the molecular basis of human disease remains an unsolved challenge, as 93% of disease loci are non-coding and gene-regulatory annotations are highly incomplete1–3.
Benjamin T James +2 more
exaly +2 more sources
Single-cell epigenomics reveals mechanisms of human cortical development
Nature, 2021 During mammalian development, differences in chromatin state coincide with cellular differentiation and reflect changes in the gene regulatory landscape1.
Amy B Wilfert +2 more
exaly +2 more sources
The NIH Roadmap Epigenomics Mapping Consortium
Nature Biotechnology, 2010 Bradley E Bernstein +2 more
exaly +2 more sources