Results 51 to 60 of about 1,856,030 (259)

CONSANGUINEOUS MARRIAGE AS RISK FACTOR FOR IDIOPATHIC GENERALIZED EPILEPSY (IGE)

Pakistan Armed Forces Medical Journal, 2021
Objective: To determine the significance of parental consanguinity as a risk factor for idiopathic generalized epilepsies. Study Design: Case control study.
Shumaila Rafique, Tipu Sultan, Shabir Ahmed   +2 more
doaj   +4 more sources

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events

Nature Communications
A diagnosis of epilepsy has significant consequences for an individual but is often challenging in clinical practice. Novel biomarkers are thus greatly needed.
Henrike O. Heyne, Fanny-Dhelia Pajuste, Julian Wanner, Jennifer I. Daniel Onwuchekwa, Reedik Mägi, Aarno Palotie, FinnGen, Estonian Biobank research team, Reetta Kälviainen, Mark J. Daly   +9 more
doaj   +1 more source

Long-term mortality risk of people with epilepsy who underwent seizure monitoring

Annals of Indian Academy of Neurology, 2019
Aim: The aim is to study survival outcome and sudden unexpected death in epilepsy (SUDEP) of people with epilepsy who underwent epilepsy monitoring. Subjects and Methods: Between 2000 and 2004, 558 persons were admitted to the epilepsy monitoring unit of
Shishir N Duble, V S Nandini, Ashalatha Radhakrishnan, Ramshekhar Menon, Ajith Cherian, P Sankara Sarma, Sanjeev V Thomas   +6 more
doaj   +1 more source

Electroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes

Frontiers in Neurology, 2017
Genetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized
U. Seneviratne, M. Cook, W. D'Souza
semanticscholar   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Chronotypes in Patients with Epilepsy: Does the Type of Epilepsy Make a Difference?

Behavioural Neurology, 2015
Circadian rhythms govern all biological functions. Circadian misalignment has a major impact on health. Late chronotype is a risk factor for circadian misalignment which in turn can affect the control of seizures in epilepsy patients. We compared a group
Hallie Kendis, Kelly Baron, Stephan U. Schuele, Bhavita Patel, Hrayr Attarian   +4 more
doaj   +1 more source

Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy

Epilepsia
The International League Against Epilepsy (ILAE) has updated the operational classification of epileptic seizures, building upon the framework established in 2017.
S. Beniczky, E. Trinka, E. Wirrell, F. Abdulla, Raidah Al Baradie, M. Alonso Vanegas, S. Auvin, M. B. Singh, H. Blumenfeld, Alicia Bogacz Fressola, R. Caraballo, Mar Carreño, F. Cendes, Augustina Charway, Mark Cook, Dana Craiu, B. Ezeala-Adikaibe, B. Frauscher, Jacqueline A French, M. Gule, Norimichi Higurashi, Akio Ikeda, F. Jansen, Barbara Jobst, Philippe Kahane, N. Kishk, C. S. Khoo, K. Vinayan, L. Lagae, K. Lim, A. Lizcano, A. McGonigal, K. Perez-Gosiengfiao, P. Ryvlin, N. Specchio, Michael R Sperling, Hermann Stefan, William O. Tatum, M. Tripathi, E. M. Yacubian, S. Wiebe, J. Wilmshurst, Dong Zhou, J. Cross   +43 more
semanticscholar   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Causal relations between ischemic stroke and epilepsy: A bidirectional Mendelian randomization study

Heliyon
Background: Although previous studies have reported a bidirectional relationship between ischemic stroke (IS) and epilepsy, the existence of a causal nexus and its directionality remains a topic of controversy.
Zongzhi Jiang, Yining Sun, Ziyi Wang, Songyan Liu   +3 more
doaj   +1 more source