Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Twins with temporal lobe epilepsy: genetic contributions to hippocampal sclerosis and other subtypes. [PDF]
Dang YL +6 more
europepmc +1 more source
Status epilepticus: Updates on mechanisms and treatments
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
A Clinicoradiological Series of 39 Gangliogliomas: Insights into Surgical Outcomes and Prognostic Factors. [PDF]
Mansour MA, Elsamman AK.
europepmc +1 more source
The multiple hit model of infantile and epileptic spasms: The 2025 update
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Clinical Trials Examining Deep Brain Stimulation for the Treatment of Epilepsy: An Analysis of the Current State. [PDF]
Gould J, Patel S, Chaurasia B.
europepmc +1 more source
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki +9 more
wiley +1 more source
Laser interstitial thermal therapy with a previously implanted responsive neurostimulation device: a multicenter experience. Illustrative cases. [PDF]
Jaffee S +4 more
europepmc +1 more source
A multi‐feature method for real‐time seizure detection in pediatric intensive care unit
Abstract Purpose Continuous electroencephalogram (cEEG) monitoring is an important technique used in detecting electroclinical seizures in the pediatric intensive care unit (PICU). This study developed an artificial intelligence method for the real‐time automatic detection of seizures in the PICU.
Tian Sang +10 more
wiley +1 more source
A case of neurosarcoidosis presenting as hippocampal sclerosis: Clinicopathological correlation and proposed mechanistic link. [PDF]
Rahimian E +8 more
europepmc +1 more source

