Results 121 to 130 of about 1,805,931 (298)

Peripheral inflammatory markers and metabolic profiles in temporal lobe epilepsy and functional dissociative seizures

open access: yesEpileptic Disorders, EarlyView.
Abstract Background Temporal lobe epilepsy (TLE) and functional dissociative seizures (FDS) are distinct conditions that share overlapping clinical, neuropsychiatric, and biological features, including depressive symptoms, obesity‐related metabolic dysregulation, and alterations in systemic inflammatory markers.
Betül Merd   +4 more
wiley   +1 more source

The burden of the postictal state in epilepsy: A prospective, single‐center observational cohort study

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu   +2 more
wiley   +1 more source

Genetic testing among patients evaluated for epilepsy surgery

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Genetic testing performed to identify the underlying etiology of epilepsy has become increasingly common and is now being recommended as part of the presurgical evaluation for epilepsy surgery. This study aimed to characterize the types of genetic tests performed in patients evaluated for epilepsy surgery and assess how genetic ...
Anni Saarela   +7 more
wiley   +1 more source

P-glycoprotein expression and function in patients with temporal lobe epilepsy: A case-control study

open access: yes, 2013
Background Studies in rodent models of epilepsy suggest that multidrug efflux transporters at the blood–brain barrier, such as P-glycoprotein, might contribute to pharmacoresistance by reducing target-site concentrations of antiepileptic drugs.
Brown, G.   +18 more
core   +1 more source

Timing of congruent and discordant interictal epileptiform EEG discharges in focal epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Interictal epileptiform discharges (IEDs) can provide additional information for localizing the epileptogenic zone (EZ). However, due to the brevity of routine electroencephalography, IEDs are often not recorded and there is a lack of general recommendation regarding the recording duration Methods In our study, we analyzed the mean ...
Katharina Ernst   +4 more
wiley   +1 more source

Occipital irregular delta activity in focal epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Nonspecific occipital irregular delta activity (OID) is a common finding in focal epilepsy (FE). However, the significance of OID and its relationship to the underlying etiology of FE remain largely unstudied. This study aimed to investigate the relationship between OID and the etiology of FE, as well as the relationship between OID ...
Mónika Bessenyei   +3 more
wiley   +1 more source

Drug-resistant frontal lobe epilepsy: A review

open access: yesSAGE Open Medicine
Drug-resistant frontal lobe epilepsy is a challenge in epilepsy surgery because it is the second most common epilepsy type after temporal lobe epilepsy.
Mohammed Alshurem
doaj   +1 more source

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