Results 161 to 170 of about 97,043 (300)
Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin +10 more
wiley +1 more source
Beyond the Usual Suspects: Cerebellar Involvement in Epilepsy. [PDF]
Lau LA.
europepmc +1 more source
Abstract Objective Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion‐weighted magnetic resonance imaging (DWI).
Peter N. Taylor +9 more
wiley +1 more source
Bitemporal Lobe Epilepsy: Evolving Diagnostic and Treatment Paradigms. [PDF]
Suller Marti A +6 more
europepmc +1 more source
Abstract Objective Anterior temporal lobe resection (ATLR) is an effective treatment for drug‐resistant temporal lobe epilepsy (TLE) but carries a substantial risk of language impairment, particularly in naming. Understanding and predicting the impact of ATLR on language functions remains a major clinical challenge.
Karl‐Heinz Nenning +8 more
wiley +1 more source
Alterations in glymphatic system and brain morphology in patients with temporal lobe epilepsy. [PDF]
Huang X +7 more
europepmc +1 more source
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers +13 more
wiley +1 more source
Co-morbid seizures in frontotemporal dementia: MRI and PET correlations. [PDF]
Hashmi SA +6 more
europepmc +1 more source
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh +10 more
wiley +1 more source

