The Dentate Gyrus and Temporal Lobe Epilepsy: An “Exciting” Era
Epilepsy Currents, 2019 This review describes developments in epilepsy research during the last 3 to 4 decades that focused on the dentate gyrus (DG) and its role in temporal lobe epilepsy (TLE).
H. Scharfman
semanticscholar +1 more source
Memory Rehabilitation Strategies in Nonsurgical Temporal Lobe Epilepsy: A Review [PDF]
, 2017 open8siPeople with temporal lobe epilepsy (TLE) who have not undergone epilepsy surgery often complain of memory deficits. Cognitive re- habilitation is employed as a remedial intervention in clinical settings, but research is limited and findings ...
Alderighi, Marzia +7 more
core +2 more sources
Left temporal lobe language network connectivity in temporal lobe epilepsy
Brain : a journal of neurology, 2018 Impairment of naming function is a critical problem for temporal lobe epilepsy patients, yet the neural correlates of the disruption of temporal lobe language networks are poorly understood.
K. Trimmel +6 more
semanticscholar +1 more source
Memory reorganization following anterior temporal lobe resection: a longitudinal functional MRI study [PDF]
, 2013 Anterior temporal lobe resection controls seizures in 50-60% of patients with intractable temporal lobe epilepsy but may impair memory function, typically verbal memory following left, and visual memory following right anterior temporal lobe resection ...
Bonelli, SB +8 more
core
Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery [PDF]
, 2016 Background The relationship between monogenic and polygenic forms of epilepsy is poorly understood, and the extent to which the genetic and acquired epilepsies share common pathways is unclear.
Danis, Bénédicte +14 more
core +9 more sources
Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons [PDF]
, 2020 OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is ...
Jansen, Laura A +3 more
core +2 more sources
Эпилепсия и пароксизмальные состояния, 2022 Background. Detected temporal lobe focal cortical dysplasia (FCD) often results in developing drug-resistant epilepsy requiring surgical treatment. In turn, temporal lobectomy, despite its high efficiency, can cause a certain deficit associated with ...
A. A. Sufianov +7 more
doaj +1 more source
Nomograms to predict naming decline after temporal lobe surgery in adults with epilepsy
Neurology, 2018 Objective To develop and externally validate models to predict the probability of postoperative naming decline in adults following temporal lobe epilepsy surgery using easily accessible preoperative clinical predictors.
R. Busch +11 more
semanticscholar +1 more source
The white matter connectome as an individualized biomarker of language impairment in temporal lobe epilepsy. [PDF]
, 2019 ObjectiveThe distributed white matter network underlying language leads to difficulties in extracting clinically meaningful summaries of neural alterations leading to language impairment.
Bahrami, Naeim +10 more
core +2 more sources
Mesial temporal sclerosis presented with refractory seizure
APIK Journal of Internal Medicine, 2019 Background: Refractory complex partial seizures are common in temporal lobe epilepsy, which is often associated with sclerosis of the structures of the medial temporal lobes, particularly the hippocampus.
Malav Patel +3 more
doaj +1 more source