Results 21 to 30 of about 73,639 (264)
Phenotypic analysis of catastrophic childhood epilepsy genes
Communications Biology, 2021 Griffin et al used CRISPR-Cas9 to generate 40 single-gene mutant zebrafish lines representing childhood epilepsies for which they evaluated larval phenotypes using electrophysiological, behavioral, neuro-anatomical, survival and pharmacological assays ...
Aliesha Griffin +12 more
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Epilepsy surgery in patient with monogenic epilepsy related to SCN8A mutation
Epilepsy & Behavior Reports, 2022 Epilepsy surgery is superior to prolonged medical therapy in patients with drug-resistant focal epilepsy, but reports on epilepsy surgery outcomes for patients with a genetic etiology are limited, especially in adults. This is the first documented report
Irina Podkorytova +3 more
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Presurgical epilepsy evaluation and epilepsy surgery [PDF]
F1000Research, 2019 With a prevalence of 0.8 to 1.2%, epilepsy represents one of the most frequent chronic neurological disorders; 30 to 40% of patients suffer from drug-resistant epilepsy (that is, seizures cannot be controlled adequately with antiepileptic drugs). Epilepsy surgery represents a valuable treatment option for 10 to 50% of these patients.
Christoph Baumgartner +4 more
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Language recovery after epilepsy surgery of the Broca's area
Epilepsy and Behavior Case Reports, 2018 Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery.
Lilit Mnatsakanyan +6 more
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Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy
Frontiers in Veterinary Science, 2021 Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. However, there are few reports of intracranial epilepsy surgery for naturally occurring epilepsy in veterinary medicine.
Daisuke Hasegawa +8 more
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Scientific Reports, 2023 Age at onset of epilepsy is an important predictor of deterioration in naming ability following epilepsy surgery. In 141 patients with left hemispheric epilepsy and language dominance who received epilepsy surgery at the Epilepsy Centre Erlangen, naming ...
Caroline Reindl +17 more
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Biomedical Journal, 2021 Backgrounds: Epilepsy surgery is the most efficacious therapeutic modality for patients with medical refractory epilepsy, especially resective surgery. However, the variable etiologies and multiple epileptic foci are usually associated with the outcomes.
Hsiang-Yao Hsieh +12 more
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National Epilepsy Surgery Support Activity
Annals of Indian Academy of Neurology, 2014 While there are over one million people with drug-resistant epilepsy in India, today, there are only a handful of centers equipped to undertake presurgical evaluation and epilepsy surgery.
K Radhakrishnan +2 more
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Scientific Reports, 2023 The temporal pole (TP) plays a central role in semantic memory, yet its neural machinery is unknown. Intracerebral recordings in patients discriminating visually the gender or actions of an actor, yielded gender discrimination responses in the ...
P. Tiesinga +5 more
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Research progress on common pathological types of somatic mutation in epilepsy surgery
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Epilepsy is a common neurological disease in clinic. Epilepsy caused by structural causes can be cured by surgery, which has been the focus of attention in the field of epilepsy surgery.
LI Zi⁃lin, HU Wen⁃han, ZHANG Kai
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