Results 31 to 40 of about 1,603,653 (309)

Phenotypic analysis of catastrophic childhood epilepsy genes

open access: yesCommunications Biology, 2021
Griffin et al used CRISPR-Cas9 to generate 40 single-gene mutant zebrafish lines representing childhood epilepsies for which they evaluated larval phenotypes using electrophysiological, behavioral, neuro-anatomical, survival and pharmacological assays ...
Aliesha Griffin   +12 more
doaj   +1 more source

Recent Aspects of Pediatric Epilepsy Surgery [PDF]

open access: yes, 2019
Surgery has been and is now a well-established treatment indicated for adults and children with drug-resistant epilepsy (DRE). The surgical landscape for children with DRE appears to be expanding, and surgical cases of pediatric epilepsy have increased ...
김흥동
core   +1 more source

Presurgical epilepsy evaluation and epilepsy surgery [PDF]

open access: yesF1000Research, 2019
With a prevalence of 0.8 to 1.2%, epilepsy represents one of the most frequent chronic neurological disorders; 30 to 40% of patients suffer from drug-resistant epilepsy (that is, seizures cannot be controlled adequately with antiepileptic drugs). Epilepsy surgery represents a valuable treatment option for 10 to 50% of these patients.
Christoph Baumgartner   +4 more
openaire   +2 more sources

Language recovery after epilepsy surgery of the Broca's area

open access: yesEpilepsy and Behavior Case Reports, 2018
Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery.
Lilit Mnatsakanyan   +6 more
doaj   +1 more source

Epilepsy surgery around language cortex [PDF]

open access: yes, 2009
Background. Both epilepsy surgery and surgery close to functionally significant cortical areas have challenged neurosurgeons in the last two decades.
Ribenis, Aksels
core   +1 more source

Uncovering the fast, directional signal flow through the human temporal pole during semantic processing

open access: yesScientific Reports, 2023
The temporal pole (TP) plays a central role in semantic memory, yet its neural machinery is unknown. Intracerebral recordings in patients discriminating visually the gender or actions of an actor, yielded gender discrimination responses in the ...
P. Tiesinga   +5 more
doaj   +1 more source

Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy

open access: yesFrontiers in Veterinary Science, 2021
Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. However, there are few reports of intracranial epilepsy surgery for naturally occurring epilepsy in veterinary medicine.
Daisuke Hasegawa   +8 more
doaj   +1 more source

National Epilepsy Surgery Support Activity

open access: yesAnnals of Indian Academy of Neurology, 2014
While there are over one million people with drug-resistant epilepsy in India, today, there are only a handful of centers equipped to undertake presurgical evaluation and epilepsy surgery.
K Radhakrishnan   +2 more
doaj   +1 more source

Aggressive cytoreduction and multiple subpial cortical transections may obtain good surgical outcomes in refractory epilepsy with multiple epileptic foci

open access: yesBiomedical Journal, 2021
Backgrounds: Epilepsy surgery is the most efficacious therapeutic modality for patients with medical refractory epilepsy, especially resective surgery. However, the variable etiologies and multiple epileptic foci are usually associated with the outcomes.
Hsiang-Yao Hsieh   +12 more
doaj   +1 more source

Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence [PDF]

open access: yes, 2011
Marco Mula1, Dale C Hesdorffer21Department of Clinical and Experimental Medicine, Amedeo Avogadro University and Division of Neurology, University Hospital Maggiore della Carità, Novara, Italy; 2Gertrude H Sergievsky Center and Department of ...
Mula M   +3 more
core   +1 more source

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