Results 51 to 60 of about 1,687,814 (309)

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Relation of Structural and Functional Changes in Auditory and Visual Pathways after Temporal Lobe Epilepsy Surgery

open access: yesBehavioral Sciences, 2018
Auditory and visual pathways may be affected as a consequence of temporal lobe epilepsy surgery because of their anatomical relationships with this structure.
Margarita Minou Báez-Martín   +16 more
doaj   +1 more source

Simple partial status epilepticus manifested as homonymous hemianopsia: a rare intracranial recording

open access: yesClinics and Practice, 2016
A 30-year-old woman with intractable seizures evaluated as surgical candidate. During presurgical evaluation an invasive electroencephalogram was recommended to define the location and extent of epileptogenic zone and relationship to epileptogenic lesion.
Anna Siatouni   +7 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Insular epilepsy surgery [PDF]

open access: yesEpilepsia, 2017
SummarySince it was originally described nearly 70 years ago, insular epilepsy has been increasingly recognized and may explain failures after apparently well‐planned operations. We review the history of awareness of the phenomenon, techniques for its assessment, and its surgical management.
Pramote, Laoprasert   +2 more
openaire   +2 more sources

Epilepsy due to Intracranial Surgery: 15 Years of Experience

open access: yes, 2017
Objectives: Epidemiological studies have shown increased incidence of epilepsy in cases of brain trauma, central nervous system infection, cerebrovascular disease (CVD), and brain tumors. Etiology of epilepsy varies according to age.
Ilhan Algin, Demet   +7 more
core   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection [PDF]

open access: yes, 2010
Functional magnetic resonance imaging can demonstrate the functional anatomy of cognitive processes. In patients with refractory temporal lobe epilepsy, evaluation of preoperative verbal and visual memory function is important as anterior temporal lobe ...
Thompson, P. J.   +7 more
core  

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Identifying epilepsy surgery referral candidates with natural language processing in an Australian context

open access: yesEpilepsia Open
Objective Epilepsy surgery is known to be underutilized. Machine learning‐natural language processing (ML‐NLP) may be able to assist with identifying patients suitable for referral for epilepsy surgery evaluation.
Sheryn Tan   +15 more
doaj   +1 more source

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