Results 11 to 20 of about 146,603 (292)

Detection of epileptic spasms using foundational AI and smartphone videos. [PDF]

NPJ Digit Med
Infantile epileptic spasm syndrome (IESS) is a severe neurological disorder characterized by epileptic spasms (ES). Timely diagnosis is crucial, but it is often delayed due to symptom misidentification.
Miron G, Halimeh M, Tietze S, Holtkamp M, Meisel C.   +4 more
europepmc   +2 more sources

Epileptic spasms in infants: can video-EEG reveal the disease’s etiology? A retrospective study and literature review

Frontiers in Neurology, 2023
ObjectiveEpileptic spasms are a type of seizure defined as a sudden flexion or extension predominantly of axial and/or truncal limb muscles that occur with a noticeable periodicity. Routine electroencephalogram supports the diagnosis of epileptic spasms,
Raffaele Falsaperla, Raffaele Falsaperla, Sarah Sciuto, Grete Francesca Privitera, Lucia Giovanna Tardino, Giuseppe Costanza, Alessandra Di Nora, Roberto Horacio Caraballo, Martino Ruggieri   +8 more
doaj   +2 more sources

Epileptic spasms as the presenting seizure type in a patient with a new “O” of TORCH, congenital Zika virus infection

Epilepsy and Behavior Case Reports, 2019
Congenital TORCH infections are a significant cause of epileptic spasms, an infantile epileptic encephalopathy, through disruptions to several pathways in neurodevelopment. Congenital Zika virus has a similar neurotropism to other TORCH agents, and leads
Jason Lockrow, Hannah Tully, Russell P. Saneto   +2 more
doaj   +2 more sources

Different pharmacoresistance of focal epileptic spasms, generalized epileptic spasms, and generalized epileptic spasms combined with focal seizures [PDF]

Epilepsia Open, 2022
Objective Among standard treatments for infantile spasms, adrenocorticotropic hormone (ACTH) is reported as the best treatment, but ACTH is ineffective in one‐half of the patients.
Yukitoshi Takahashi, Akiko Ota, Jun Tohyama, Tomoko Kirino, Yumi Fujiwara, Chizuru Ikeda, Shigeki Tanaka, Jyunya Takahashi, Toshihiko Shinoki, Hiroshi Shiraga, Takushi Inoue, Hiroshi Fujita, Motoki Bonno, Masayoshi Nagao, Hideo Kaneko   +14 more
doaj   +2 more sources

Ketogenic diets therapy in the management of epileptic spasms syndrome. [PDF]

Front Pediatr
Infantile Epileptic Spasm Syndrome (IESS) is a group of infantile spasm syndromes of various etiologies that typically present in early infancy, predispose to refractory epilepsy, and leave intellectual disability.
Wang M, Zhao F, Sun L, Yu Y, Zhang H.
europepmc   +2 more sources

Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids

EBioMedicine, 2022
Summary: Background: Epileptic (previously infantile) spasms is the most common epileptic encephalopathy occurring during infancy and is frequently associated with abnormal neurodevelopmental outcomes.
Jingya Yan, Kavitha Kothur, Emily A. Innes, Velda X. Han, Hannah F. Jones, Shrujna Patel, Erica Tsang, Richard Webster, Sachin Gupta, Christopher Troedson, Manoj P. Menezes, Jayne Antony, Simone Ardern-Holmes, Esther Tantsis, Shekeeb Mohammad, Louise Wienholt, Ananda S. Pires, Benjamin Heng, Gilles J. Guillemin, Anna Guller, Deepak Gill, Sushil Bandodkar, Russell C. Dale   +22 more
doaj   +2 more sources

Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]

Frontiers in Pediatrics
BackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen, Henry Chen, Adam L. Numis, Adam L. Numis, Renée A. Shellhaas, John R. Mytinger, Debopam Samanta, Rani K. Singh, Rani K. Singh, Shaun A. Hussain, Danielle Takacs, Kelly G. Knupp, Li-Rong Shao, Carl E. Stafstrom   +13 more
doaj   +2 more sources

Genetic Advancements in Infantile Epileptic Spasms Syndrome and Opportunities for Precision Medicine. [PDF]

Genes (Basel)
Infantile epileptic spasms syndrome (IESS) is a devastating developmental epileptic encephalopathy (DEE) consisting of epileptic spasms, as well as one or both of developmental regression or stagnation and hypsarrhythmia on EEG.
Snyder HE, Jain P, RamachandranNair R, Jones KC, Whitney R.   +4 more
europepmc   +2 more sources

Electrophysiological network predicts clinical response to vigabatrin in epileptic spasms. [PDF]

Front Neurol, 2023
Purpose This study aimed to discover electrophysiologic markers correlated with clinical responses to vigabatrin-based treatment in infants with epileptic spasms (ES).
Kim J, Kim MJ, Kim HJ, Yum MS, Ko TS.
europepmc   +2 more sources

Electroclinical Features of Infantile Epileptic Spasms Syndrome [PDF]

Annals of Indian Academy of Neurology
Epileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
doaj   +2 more sources