Results 191 to 200 of about 2,093,419 (291)

Epistemological Anatomy: A Conceptual Framework for Understanding Anatomical Knowledge

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Anatomy is often regarded as settled knowledge. Yet anatomical propositions differ enormously in their evidentiary foundations, while textbooks and atlases frequently present them with similar certainty. How, then, does an anatomical observation become anatomical knowledge? We introduce epistemological anatomy as a framework for the systematic
Marios Loukas   +5 more
wiley   +1 more source

Dynamic survival risk prediction with time‐varying high‐dimensional images

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Integrating longitudinal data with survival models is a prevalent strategy for dynamic survival risk prediction while accounting for subjects' longitudinally observed variables. However, existing methods primarily focus on scalar longitudinal data and seldom tackle the complexities associated with high‐dimensional longitudinal imaging data ...
Bingfan Liu   +7 more
wiley   +1 more source

Episodic memory retrieval with increasing task demand: associations with age, <i>APOE4</i> genotype and Alzheimer's disease pathology. [PDF]

open access: yesBrain Commun
Askevold F   +16 more
europepmc   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

open access: yesCytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham   +3 more
wiley   +1 more source

Captivated by Kinesin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
wiley   +1 more source

Intelligent Automation Improved Efficiency in Pharmacovigilance Safety Signal Assessment

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacovigilance is the science involving the detection, assessment, understanding, and prevention of adverse events associated with drugs, biologics, or medical devices. In pharmacovigilance, information that suggests a new potential causal relationship between an intervention and an adverse event is called a safety signal. Following their detection,
Jeffrey Warner   +3 more
wiley   +1 more source

Firm‐Level Corporate Social Responsibility and Employees' Affective Outcomes: A Multilevel Approach

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study advances research on corporate social responsibility (CSR) and employees' work attitudes by distinguishing between employee‐level CSR perceptions and firm‐level CSR practices. Prior research has mainly focused on how employees' perceptions of CSR relate to their affective outcomes; this study extends that perspective by jointly ...
Alexander C. Kraaij   +2 more
wiley   +1 more source

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