Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie +10 more
wiley +1 more source
Stereo‐EEG mapping of visual working memory with task‐related high‐gamma modulations
Abstract Objective We describe a safe, informative, and easy‐to‐implement approach for presurgical mapping of visual working memory (VWM) with stereo‐electroencephalography (SEEG). Methods Twenty‐four patients with drug‐resistant epilepsy, 11–23 years of age, performed a single‐probe change detection VWM task, during SEEG monitoring.
Brian Ervin +13 more
wiley +1 more source
Abstract Objective Circulating small noncoding RNAs represent potential biomarkers of temporal lobe epilepsy (TLE). Recently, two transfer RNA fragments (tRFs), 5′tRF Glu‐CTC and Gly‐GCC, were found to be elevated in plasma samples collected in advance of a seizure in TLE patients, suggesting they may serve as potential wet biomarkers of seizure risk ...
Marie Soukupova +15 more
wiley +1 more source
Contributions of Gray Matter Microstructure to Differences in Fluid Cognition and Episodic Memory Across the Healthy Adult Lifespan. [PDF]
Merenstein JL, Bennett IJ, Madden DJ.
europepmc +1 more source
Tonic–clonic seizures captured during ambulatory video‐EEG are frequently unreported
Abstract Objective Tonic–clonic seizures (TCSs) are widely regarded as clinically obvious, yet seizure counts used for treatment decisions and risk counseling often rely on patient or caregiver diaries. We sought to quantify the frequency of unreported TCSs during prolonged ambulatory video‐EEG (vEEG) monitoring and examined associations with ...
Ewan S. Nurse +3 more
wiley +1 more source
Episodic Memory in Amnestic Mild Cognitive Impairment at Risk for Alzheimer's Disease: Spanish Validation of the TYM-MCI. [PDF]
Belmar-Moreno Á +10 more
europepmc +1 more source
The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg +9 more
wiley +1 more source
Creativity and its link to epilepsy
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges +4 more
wiley +1 more source
The importance of modifiable lifestyle factors for episodic memory: a gradient boosted tree analysis. [PDF]
Berg AL +7 more
europepmc +1 more source

