Results 121 to 130 of about 48,693 (213)

Correction: From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

PLoS Genetics, 2008
Table 1b is not displayed correctly in the published article. Please see the correct Table 1 here:
David L. Aylor, Zhao-Bang Zeng
openaire   +4 more sources

Orthogonal Decomposition of the Genetic Variance for Epistatic Traits Under Linkage Disequilibrium—Applications to the Analysis of Bateson-Dobzhansky-Müller Incompatibilities and Sign Epistasis

Frontiers in Genetics, 2019
The one-century-old theory of orthogonal genetic variance decomposition originated the field of quantitative genetics and has kept on being improved ever since.
José M. Álvarez-Castro, Rosa M. Crujeiras   +1 more
doaj   +1 more source

Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies

BioData Mining, 2019
Background In Genome-Wide Association Studies (GWAS), the concept of linkage disequilibrium is important as it allows identifying genetic markers that tag the actual causal variants.
Marc Joiret, Jestinah M. Mahachie John, Elena S. Gusareva, Kristel Van Steen   +3 more
doaj   +1 more source

Epistasis and Shapes of Fitness Landscapes [PDF]

, 2006
The relationship between the shape of a fitness landscape and the underlying gene interactions, or epistasis, has been extensively studied in the two-locus case. Gene interactions among multiple loci are usually reduced to two-way interactions.
Beerenwinkel, Niko, Pachter, Lior, Sturmfels, Bernd   +2 more
core   +4 more sources

Privacy-preserving decision tree for epistasis detection

Cybersecurity, 2019
The interaction between gene loci, namely epistasis, is a widespread biological genetic phenomenon. In genome-wide association studies(GWAS), epistasis detection of complex diseases is a major challenge. Although many approaches using statistics, machine
Qingfeng Chen, Xu Zhang, Ruchang Zhang
doaj   +1 more source

Transgressive segregation affects essential oil composition in a model mint population

New Phytologist, Volume 247, Issue 4, Page 1564-1571, August 2025.
B. Markus Lange, Amber N. Parrish, Iris Lange, Yanmei Xiao, Iovanna Pandelova, Haixiao Dong, Zhiwu Zhang, Sümeyye Carkit‐Yilmaz, Thomas M. Davis, Matthias Wüst, Narayanan Srividya, Kelly J. Vining   +11 more
wiley   +1 more source

'On the Application of Hierarchical Coevolutionary Genetic Algorithms: Recombination and Evaluation Partners' [PDF]

, 2003
This paper examines the use of a hierarchical coevolutionary genetic algorithm under different partnering strategies. Cascading clusters of sub-populations are built from the bottom up, with higher-level sub-populations optimising larger parts of the ...
Aickelin, Uwe, Bull, Larry
core   +5 more sources

Distributed transformer for high order epistasis detection in large-scale datasets

Scientific Reports
Understanding the genetic basis of complex diseases is one of the most important challenges in current precision medicine. To this end, Genome-Wide Association Studies aim to correlate Single Nucleotide Polymorphisms (SNPs) to the presence or absence of ...
Miguel Graça, Ricardo Nobre, Leonel Sousa, Aleksandar Ilic   +3 more
doaj   +1 more source

Reducing Epistasis and Pleiotropy Can Avoid the Survival of the Flattest Tragedy

Biology
This study investigates whether reducing epistasis and pleiotropy enhances mutational robustness in evolutionary adaptation, utilizing an indirect encoded model within the “survival of the flattest” (SoF) fitness landscape.
Priyanka Mehra, Arend Hintze
doaj   +1 more source

THE EFFECT OF EPISTASIS AND GAMETIC UNBALANCE ON GENETIC LOAD [PDF]

Genetics, 1966
S. K. Jain, R. W. Allard, P. E. Hansche
openaire   +3 more sources