Results 131 to 140 of about 27,549 (205)

How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution.

Chem Soc Rev
Kell DB, Roberts I.
europepmc   +1 more source

Sign Epistasis Can be Absent in Multi-peaked Landscapes With Neutral Mutations. [PDF]

Genome Biol Evol
Ivankov DN, Zorin EM.
europepmc   +1 more source

Predicting the topography of fitness landscapes from the structure of genotype-phenotype maps. [PDF]

Genetics
Srivastava M, Louis AA, Martin NS.
europepmc   +1 more source

Epistasis and background dependence in the evolution of Omicron variants of the SARS-CoV-2 spike protein. [PDF]

Mol Biol Evol
Moulana A, Dupic T, Desai MM.
europepmc   +1 more source

Epistasis [PDF]

, 2019
openaire   +1 more source

A biobank-scale test of marginal epistasis reveals genome-wide signals of polygenic interaction effects. [PDF]

Nat Genet
Fu B, Pazokitoroudi A, Shi Z, Kar A, Xue A, Anand A, Anand P, Liu Z, Border R, Pajukanta P, Zaitlen N, Sankararaman S.   +11 more
europepmc   +1 more source

Background selection in recombining genomes and its consequences for the maintenance of variation in complex traits. [PDF]

Proc Natl Acad Sci U S A
Li X, Berg JJ.
europepmc   +1 more source

Lifespan and Fecundity Impacts of Reduced Insulin Signalling Can Be Directed by Mito-Nuclear Epistasis in Drosophila. [PDF]

Aging Cell
Ibrahim R, Froschauer C, Broschk S, Sannino DR, Dobson AJ.   +4 more
europepmc   +1 more source

D-LIM: A neural network for interpretable gene-gene interactions. [PDF]

PLoS Comput Biol
Wang S, Allauzen A, Nghe P, Opuu V.
europepmc   +1 more source

Epistasis in colour [PDF]

Nature Reviews Genetics, 2005
openaire   +1 more source