Results 191 to 200 of about 37,358 (239)

Epistatic impacts of cis- and trans-regulatory mutations on the distribution of mutational effects for gene expression in Saccharomyces cerevisiae. [PDF]

Mol Biol Evol
McQueen E, Yang B, Wittkopp PJ.
europepmc   +1 more source

Asperger Traits as a Conditionally Adaptive Neurocognitive Phenotype: An Evolutionary Narrative Review. [PDF]

Cureus
Bertuccioli A, Belli A, Palazzi CM, Di Pierro F, Cavecchia I, Matera M.   +5 more
europepmc   +1 more source

Genetic architecture of angular leaf spot resistance in cultivated strawberry shaped by epistasis and genotype-by-environment interactions. [PDF]

Plant Genome
Torgeman S, Pincot DDA, Bjornson M, Famula RA, Skillin P, Krill-Brown A, Feldmann MJ.   +6 more
europepmc   +1 more source

How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution.

Chem Soc Rev
Kell DB, Roberts I.
europepmc   +1 more source

Describing the persistence landscape for introducing microbes into complex communities. [PDF]

Appl Environ Microbiol
McDermott JE, Nelson WC, Zimmerman AE, Anthony W, Coleman-Derr D, Elmore JR, Nitka T, McClure RS, Handakumbura PP, Guss AM, Wheeler TJ, Egbert RG.   +11 more
europepmc   +1 more source

Phantom epistasis through the lens of genealogies. [PDF]

Genetics
Ignatieva A, Ferreira LAF.
europepmc   +1 more source

Interchromosomal linkage disequilibrium analysis reveals strong indications of sign epistasis in wheat breeding families. [PDF]

G3 (Bethesda)
Tessele A, Morris G, Akhunov E, Johnson B, Clinesmith M, Hope AC, Fritz A.   +6 more
europepmc   +1 more source

Inferring genotype-phenotype maps using attention models. [PDF]

PNAS Nexus
Rijal K, Holmes CM, Petti S, Reddy G, Desai MM, Mehta P.   +5 more
europepmc   +1 more source

The causes of epistasis [PDF]

Proceedings of the Royal Society B: Biological Sciences, 2011
Since Bateson's discovery that genes can suppress the phenotypic effects of other genes, gene interactions—called epistasis—have been the topic of a vast research effort.
Timothy F. Cooper, Santiago F. Elena, JAGM   +2 more
exaly   +6 more sources

PERSPECTIVE:SIGN EPISTASIS AND GENETIC CONSTRAINT ON EVOLUTIONARY TRAJECTORIES

Evolution; International Journal of Organic Evolution, 2005
Epistasis for fitness means that the selective effect of a mutation is conditional on the genetic background in which it appears. Although epistasis is widely observed in nature, our understanding of its consequences for evolution by natural selection ...
Lin Chao, Richard A Watson, Daniel Weinreich   +2 more
exaly   +2 more sources