Results 201 to 210 of about 37,358 (239)

Dynamics in Epistasis Analysis

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018
Finding regulatory relationships between genes, including the direction and nature of influence between them, is a fundamental challenge in the field of molecular genetics. One classical approach to this problem is epistasis analysis. Broadly speaking, epistasis analysis infers the regulatory relationships between a pair of genes in a genetic pathway ...
Aseel Awdeh, Hilary Phenix, Mads Kærn, Theodore J. Perkins   +3 more
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Symbolic Modeling of Epistasis

Human Heredity, 2007
The workhorse of modern genetic analysis is the parametric linear model. The advantages of the linear modeling framework are many and include a mathematical understanding of the model fitting process and ease of interpretation. However, an important limitation is that linear models make assumptions about the nature of the data being modeled.
Jason H, Moore, Nate, Barney, Chia-Ti, Tsai, Fu-Tien, Chiang, Jiang, Gui, Bill C, White   +5 more
openaire   +2 more sources

Epistasis in Neuropsychiatric Disorders

Trends in Genetics, 2017
The contribution of epistasis to human disease remains unclear. However, several studies have now identified epistatic interactions between common variants that increase the risk of a neuropsychiatric disorder, while there is growing evidence that genetic interactions contribute to the pathogenicity of rare, multigenic copy-number variants (CNVs) that ...
openaire   +2 more sources

Epistasis

2013
Lara LaCaille, Anna Maria Patino-Fernandez, Jane Monaco, Ding Ding, C. Renn Upchurch Sweeney, Colin D. Butler, Colin L. Soskolne, Yori Gidron, Yori Gidron, J. Rick Turner, J. Rick Turner, Jorie Butler, Michelle Nicole Burns, David C. Mohr, Ivan Molton, Douglas Carroll, Hugo Critchley, Yoko Nagai, Linda C. Baumann, Alyssa Karel, Michelle Skinner, Michelle Skinner, Pamela S. King, Pamela S. King, Linda C. Baumann, Alyssa Karel, Siqin Ye, Karen Jacobs, Miranda Hellman, Jacqueline Markowitz, Ellen Wuest, Mann Hyung Hur, Janine Sanchez, Andrea Croom, James A. McCubbin, Beate Ditzen, Friedrich Wieser, Robert N. Taylor, Jet Veldhuijzen Zanten, Quinn D. Kellerman, Jennifer Heaney, Marc D. Gellman, G. David Batty, Alicia K. Smith, James W. Schroeder, George J. Trachte, Deidre Pereira, Seema M. Patidar, Catherine Benedict, Urs M. Nater, Sheah Rarback, Maurizio Cutolo, Yoshiyuki Takimoto, Yoshiyuki Takimoto, Jane Upton, Kristine M. Molina, Orit Birnbaum-Weitzman, Michael Witthöft, Kristin Kilbourn, Shannon Madore, Bonnie Spring, Molly Ferguson, Stephanie Russell, Alyson Sularz, Megan Roehrig, Peter A. Hall, Jordan Carlson, Alexandre Morizio, Simon Bacon, J. Rick Turner, J. Rick Turner, J. Rick Turner, Yori Gidron, Yori Gidron, Stephen J. Lepore, Wendy Kliewer, Marcia D. McNutt, Monica Webb Hooper, Gary Davis, Kevin S. Masters, Naum Purits, Ingrid Söderback   +81 more
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Epistasis

2021
openaire   +2 more sources

Phantom epistasis between unlinked loci

Nature, 2021
Allan F McRae, Harm-Jan Westra, Joseph E Powell   +2 more
exaly  

More on epistasis

Reviews in Medical Virology, 2005
openaire   +2 more sources

Epistasis and quantitative traits: using model organisms to study gene–gene interactions

Nature Reviews Genetics, 2013
Trudy Mackay
exaly  

Detecting epistasis in human complex traits

Nature Reviews Genetics, 2014
Wenhua Wei, Chris Haley, Gibran Hemani
exaly  

PERSPECTIVE: SIGN EPISTASIS AND GENETIC COSTRAINT ON EVOLUTIONARY TRAJECTORIES

Evolution; International Journal of Organic Evolution, 2005
Lin Chao, Richard A Watson, Daniel Weinreich   +2 more
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