Results 111 to 120 of about 220,774 (295)

YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma [PDF]

, 2018
Xin Zhang, Xuehai Wang, Ran Xu, Jianxiong Ji, Yangyang Xu, Mingzhi Han, Yuzhen Wei, Bin Huang, Anjing Chen, Qing Zhang, Wenjie Li, Jian Wang, Xingang Li, Chen Qiu   +13 more
openalex   +1 more source

ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer [PDF]

, 2020
Dian Liu, Ayse Ertay, Charlotte Hill, Yilu Zhou, Juanjuan Li, Yanmei Zou, Hong Qiu, Xianglin Yuan, Rob M. Ewing, Xin Lü, Hua Xiong, Yihua Wang   +11 more
openalex   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Epithelial-Mesenchymal Transition Markers in Breast Cancer and Pathological Responseafter Neoadjuvant Chemotherapy [PDF]

, 2018
Shaimaa Elzamly, Nabeel Badri, Osvaldo Padilla, Alok Dwivedi, Luis Alvarado, Matthew J. Hamilton, Nabih Diab, Crosby D. Rock, Ahmed Elfar, Marwa Teleb, Luis A. Sánchez, Zeina Nahleh   +11 more
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior [PDF]

, 2019
C. Dilara Savci‐Heijink, Hans Halfwerk, Gerrit K. Hooijer, Jan Köster, Hugo M. Horlings, Sybren L. Meijer, Marc J. van de Vijver   +6 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Tracing the origin of myofibroblasts in kidney fibrosis

Nature Communications
Kidney fibrosis is a key pathological feature of chronic kidney disease (CKD), characterized by the activation and accumulation of αSMA-positive myofibroblasts.
Shun He, Tianchang Xia, Zhihou Guo, Xin Song, Haichang Wang, Haojie He, Ke Jia, Raodan Chen, Bin Zhou, Lingjuan He   +9 more
doaj   +1 more source

<p>AHNAK2 Promotes Migration, Invasion, and Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Cells via the TGF-β/Smad3 Pathway</p>

, 2020
Gang Liu, Zhongliang Guo, Qian Zhang, Zhongmin Liu, Dongyi Zhu   +4 more
openalex   +2 more sources