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The epithelial–mesenchymal transition (EMT) phenomenon
The epithelial-mesenchymal transition (EMT) describes a rapid and often reversible modulation of phenotype by epithelial cells. EMT was originally defined in the context of developmental stages, including heart morphogenesis, mesoderm and neural crest formation. Epithelial cells loosen cell-cell adhesion structures throughout EMT.
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N-Cadherin Expression and Epithelial-Mesenchymal Transition in Pancreatic Carcinoma [PDF]
Sanae Nakajima+13 more
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Colorectal cancer is a leading cause of cancer-related mortality worldwide. Traditionally, colorectal cancer has been recognized as a disease caused by genetic mutations.
Yingnan Wang, Yufan Chen, Miaomiao Zhao
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Epithelial-mesenchymal transition in glioblastoma progression
Epithelial-mesenchymal transition (EMT) is a reversible biological process that occurs in epithelial cells. EMT ultimately leads to the acquisition of a mesenchymal phenotype, characterized by increased cell motility and resistance to genotoxic agents.
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Transient Overexpression of TGF-β1 Induces Epithelial Mesenchymal Transition in the Rodent Peritoneum [PDF]
Peter J. Margetts+6 more
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SnapShot: The Epithelial-Mesenchymal Transition
Sleeman, J. P., Thiery, J. P.
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Epithelial-Mesenchymal Transition: NF-κB Takes Center Stage [PDF]
Margit A. Huber+2 more
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Tumor Metastasis: A New Twist on Epithelial–Mesenchymal Transitions [PDF]
Ann E. Vernon, Carole LaBonne
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Objective: Previous studies have demonstrated synergistic antitumor effects of angiotensin system inhibition (ASI) combined with cisplatin therapy in pancreatic cancer.
Hexiao Tang, MD, PhD+8 more
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Pediatric cancer remains the leading cause of disease-related death among children aged 1–14 years. A few risk factors have been conclusively identified, including exposure to pesticides, high-dose radiation, and specific genetic syndromes, but the ...
Consolato M. Sergi
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