Results 11 to 20 of about 208,684 (264)
Cortactin in Epithelial–Mesenchymal Transition [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cortactin, a member of the actin-binding protein family, plays an important role in cell movement involving the cytoskeleton, as cell movement mediated by cortactin may induce the epithelial–mesenchymal transition.
Rong Ji +3 more
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Epithelial-Mesenchymal Transition [PDF]
Cancer Research, 2008 The meeting was designed to explore the intersections of signalling networks regulating and supporting epithelial-mesenchymal (EMT) and mesenchymal-epithelial transitions (MET) in development, fibrosis, and cancer.
Zavadil, J. +4 more
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Biomarkers for epithelial-mesenchymal transitions [PDF]
Journal of Clinical Investigation, 2009 Somatic cells that change from one mature phenotype to another exhibit the property of plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by studying the process of epithelial-mesenchymal transition (EMT).
Zeisberg, Michael, Neilson, Eric G.
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Epithelial–Mesenchymal Transition (EMT)
International Journal of Molecular Sciences, 2023 Epithelial–mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...]
Guidalberto Manfioletti, Monica Fedele
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The basics of epithelial-mesenchymal transition [PDF]
Journal of Clinical Investigation, 2009 The origins of the mesenchymal cells participating in tissue repair and pathological processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly understood. However, emerging evidence suggests that epithelial-mesenchymal transitions (EMTs) represent one important source of these cells. As we discuss here, processes similar to the
Raghu, Kalluri, Robert A, Weinberg
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Epithelial–Mesenchymal Transition (EMT) 2021
International Journal of Molecular Sciences, 2022 Epithelial–mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial cells acquire characteristics typical of mesenchymal cells [...]
Guidalberto Manfioletti, Monica Fedele
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Epithelial-mesenchymal transitions and hepatocarcinogenesis [PDF]
Journal of Clinical Investigation, 2010 Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.
Jou, Janice, Diehl, Anna Mae
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Clinical significance of epithelial‐mesenchymal transition [PDF]
Clinical and Translational Medicine, 2014 AbstractThe concept of epithelial‐mesenchymal transition (EMT), a process where cells change their epithelial towards a mesenchymal phenotype, has gained overwhelming attention especially in the cancer research community. Thousands of scientific reports investigated changes in gene, mRNA and protein expression compatible with EMT and their possible ...
Konrad Steinestel +3 more
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Role of Exosomes in Epithelial–Mesenchymal Transition
ACS Applied Bio Materials, 2023 Epithelial-mesenchymal transition (EMT) is a fundamental process driving cancer metastasis, transforming non-motile cells into a motile population that migrates to distant organs and forms secondary tumors. In recent years, cancer research has revealed a strong connection between exosomes and the EMT. Exosomes, a subpopulation of extracellular vesicles,
Bikramjit Bhattacharya +11 more
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Epithelial-mesenchymal transition [PDF]
Journal of Cell Science, 2005 The epithelial-mesenchymal transition (EMT) is an orchestrated series of events in which cell-cell and cell-extracellular matrix (ECM) interactions are altered to release epithelial cells from the surrounding tissue, the cytoskeleton is reorganized to confer the ability to move through a three-
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