Results 211 to 220 of about 207,488 (262)

THOC3 interacts with epithelial-to-mesenchymal transition to promote non-small cell lung cancer carcinoma progression through STAT3 signaling pathway. [PDF]

Transl Oncol
Ni Z, Zhou S, Zhang Y, Wang X, Yang H, Zhou H, Tao Z.   +6 more
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Plumbagin Induces Cell Cycle Arrest and Autophagy and Suppresses Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR-Mediated Pathway in Human Pancreatic Cancer Cells [Retraction]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

Pseudogenes in the carcinogenesis: epithelial-to-mesenchymal transition process and cancer initiating cells. [PDF]

Rep Pract Oncol Radiother
Kolenda T, Chałaj P, Cichowicz A, Trojańska A, Bałoniak A, Kwaśniewska M, Odrobińska M, Guglas K, Kozłowska-Masłoń J, Gieremek P, Poter P, Janiczek-Polewska M, Florczak-Substyk A, Przybyła A, Mantaj P, Regulska K, Stanisz BJ, Cybulski Z, Kazimierczak U.   +18 more
europepmc   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Plasma proteome correlations with liver stiffness in pediatric cholestasis implicate epithelial to mesenchymal transition. [PDF]

Hepatol Commun
Shneider BL, Kanchi RS, Grimm SL, Devaraj S, Emamaullee J, Schraw J, Lupo PJ, Bezerra JA, Loomes KM, Magee JC, Sokol RJ, Wang KS, Kriegermeier A, Hsu E, Molleston JP, Rosenthal P, Kohli R, Karpen SJ, Horslen SP, Jensen MK, Barbetta A, Coarfa C, Childhood Liver Disease Research Network.   +22 more
europepmc   +1 more source

Mechanical Intelligence in Bone Regeneration: Bridging Material and Cellular Memory for Enhanced Healing

Advanced Science, EarlyView.
Mechanical intelligence reframes bone regeneration as a time‐dependent coupling between material and cellular memory. Biomaterials store and release mechanical history, while cells retain prior cues and remodel the repair niche. Matching these memories to healing stages may guide stage‐specific scaffolds, sensing‐assisted prediction, mechanical dosing,
Jin Tian, Guoyou Huang, Yang Chen, Teng Ma, Bo Cheng, Feng Xu, XiaoKang Li, Pei Yang, Ting Wen   +8 more
wiley   +1 more source

Epithelial to Mesenchymal Transition Transcriptional Regulator ZEB1 in Liver Cancer: Oncogenic Roles and Therapeutic Potential. [PDF]

Int J Mol Sci
Gonzalez-Sanchez E, Roldan-Hernandez CA, Martin-Ramirez A, Garcia-Collado L, Fouassier L, Vaquero J.   +5 more
europepmc   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

HOTAIR requires epitranscriptomic modification to exert its pivotal epigenetic role in Epithelial to Mesenchymal Transition. [PDF]

Cell Death Dis
Garbo S, Minotti S, Marocco F, Quattrocchi L, Di Silverio I, Bontempi G, Strippoli R, Tripodi M, Battistelli C.   +8 more
europepmc   +1 more source