Results 231 to 240 of about 207,488 (262)
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Epigenetic Regulation of Epithelial to Mesenchymal Transition

Current Cancer Drug Targets, 2013
Epithelial-mesenchymal transition (EMT) is a vital process implemented in embryo development, organ fibrosis, and cancer metastasis. Several transcription factors and signaling pathways impinge on the transcriptional program of the cell, leading to the change of cell phenotype without alteration of genotype.
Peiwei, Huangyang, Yongfeng, Shang
openaire   +2 more sources

Phosphate Toxicity and Epithelial to Mesenchymal Transition

2022
The underlying role of inadequate or excess intake of phosphate is evident in disease states, including metabolic, skeletal, cardiac, kidney and various cancers. Elevated phosphate levels can induce epithelial to mesenchymal transition (EMT) and cell death.
Eric, Lewis   +3 more
openaire   +2 more sources

Polyamines modulate epithelial-to-mesenchymal transition

Amino Acids, 2011
Epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition are biologic processes responsible for conversion of epithelial cells into a mesenchymal phenotype or viceversa, respectively. They occur during embryo- and foetal-development and, in adult organisms, are involved in wound healing, in the genesis and progression of organ ...
Alessandra, Compagnone   +13 more
openaire   +2 more sources

Epithelial-to-mesenchymal transition in tumor progression

Medical Oncology, 2017
The epithelial-to-mesenchymal transition (EMT) is a biological process in which a non-motile epithelial cell changes to a mesenchymal state with invasive capacities. However, the EMT program is involved in both physiological and pathological processes.
Elena Prieto-García   +3 more
openaire   +2 more sources

Epithelial-to-Mesenchymal Transition in Renal Neoplasms

Advances in Anatomic Pathology, 2014
Epithelial-to-mesenchymal transition (EMT) describes a phenotypical change induced in epithelial cells that lose their cell-cell basement membrane contacts and their structural polarity to become spindle-shaped and morphologically similar to mesenchymal/myofibroblast cell.
Huiying, He, Cristina, Magi-Galluzzi
openaire   +2 more sources

Epithelial to mesenchymal transition

Critical Care Medicine, 2012
Anil K, Sharma, Rolf D, Hubmayr
  +5 more sources

Evolutionary fingerprints of epithelial-to-mesenchymal transition

Nature
Mesenchymal plasticity has been extensively described in advanced epithelial cancers; however, its functional role in malignant progression is controversial1-5. The function of epithelial-to-mesenchymal transition (EMT) and cell plasticity in tumour heterogeneity and clonal evolution is poorly understood.
Luigi Perelli   +35 more
openaire   +3 more sources

The many regulators of epithelial−mesenchymal transition

Nature Reviews Molecular Cell Biology, 2021
Cameron Bracken   +2 more
exaly  

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