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Epigenetic Regulation of Epithelial to Mesenchymal Transition
Current Cancer Drug Targets, 2013Epithelial-mesenchymal transition (EMT) is a vital process implemented in embryo development, organ fibrosis, and cancer metastasis. Several transcription factors and signaling pathways impinge on the transcriptional program of the cell, leading to the change of cell phenotype without alteration of genotype.
Peiwei, Huangyang, Yongfeng, Shang
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Phosphate Toxicity and Epithelial to Mesenchymal Transition
2022The underlying role of inadequate or excess intake of phosphate is evident in disease states, including metabolic, skeletal, cardiac, kidney and various cancers. Elevated phosphate levels can induce epithelial to mesenchymal transition (EMT) and cell death.
Eric, Lewis +3 more
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Polyamines modulate epithelial-to-mesenchymal transition
Amino Acids, 2011Epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition are biologic processes responsible for conversion of epithelial cells into a mesenchymal phenotype or viceversa, respectively. They occur during embryo- and foetal-development and, in adult organisms, are involved in wound healing, in the genesis and progression of organ ...
Alessandra, Compagnone +13 more
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Epithelial-to-mesenchymal transition in tumor progression
Medical Oncology, 2017The epithelial-to-mesenchymal transition (EMT) is a biological process in which a non-motile epithelial cell changes to a mesenchymal state with invasive capacities. However, the EMT program is involved in both physiological and pathological processes.
Elena Prieto-García +3 more
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Epithelial-to-Mesenchymal Transition in Renal Neoplasms
Advances in Anatomic Pathology, 2014Epithelial-to-mesenchymal transition (EMT) describes a phenotypical change induced in epithelial cells that lose their cell-cell basement membrane contacts and their structural polarity to become spindle-shaped and morphologically similar to mesenchymal/myofibroblast cell.
Huiying, He, Cristina, Magi-Galluzzi
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Epithelial to mesenchymal transition
Critical Care Medicine, 2012Anil K, Sharma, Rolf D, Hubmayr
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Evolutionary fingerprints of epithelial-to-mesenchymal transition
NatureMesenchymal plasticity has been extensively described in advanced epithelial cancers; however, its functional role in malignant progression is controversial1-5. The function of epithelial-to-mesenchymal transition (EMT) and cell plasticity in tumour heterogeneity and clonal evolution is poorly understood.
Luigi Perelli +35 more
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The many regulators of epithelial−mesenchymal transition
Nature Reviews Molecular Cell Biology, 2021Cameron Bracken +2 more
exaly
Peritoneal Dialysis and Epithelial-to-Mesenchymal Transition
New England Journal of Medicine, 2003openaire +2 more sources

