Results 21 to 30 of about 130,859 (259)

Characterisation of Osteopontin in an In Vitro Model of Embryo Implantation

Cells, 2019
At the onset of pregnancy, embryo implantation is initiated by interactions between the endometrial epithelium and the outer trophectoderm cells of the blastocyst.
Stéphane C Berneau, Peter T Ruane, Daniel R Brison, Susan J Kimber, Melissa Westwood, John D Aplin   +5 more
doaj   +1 more source

Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation

Scientific Reports, 2017
Integrin beta8 (ITGB8) is involved in the endometrial receptivity. The blastocyst first interacts with the luminal endometrial epithelial cells during its implantation; therefore, we have investigated the signaling of ITGB8 via FAK and VAV-RAC1 in the ...
Vijay Kumar, Upendra Kumar Soni, Vineet Kumar Maurya, Kiran Singh, Rajesh Kumar Jha   +4 more
doaj   +1 more source

EspFu-Mediated Actin Assembly Enhances Enteropathogenic Escherichia coli Adherence and Activates Host Cell Inflammatory Signaling Pathways

mBio, 2020
The translocation of effectors into the host cell through type 3 secretion systems (T3SS) is a sophisticated strategy employed by pathogenic bacteria to subvert host responses and facilitate colonization.
Fernando H. Martins, Ashwani Kumar, Cecilia M. Abe, Eneas Carvalho, Milton Nishiyama-Jr, Chao Xing, Vanessa Sperandio, Waldir P. Elias   +7 more
doaj   +1 more source

Apical Secretory Glycoprotein Complex Contributes to Cell Attachment and Entry by Cryptosporidium parvum

mBio, 2023
Cryptosporidium parvum is an enteric pathogen that invades epithelial cells in the intestine, where it resides at the apical surface in a unique epicellular location.
Marianna E. Akey, Rui Xu, Soumya Ravindran, Lisa Funkhouser-Jones, L. David Sibley   +4 more
doaj   +1 more source

Intraosseous transcutaneous amputation prostheses versus dental implants: A comparison between keratinocyte and gingival epithelial cell adhesion in vitro [PDF]

European Cells & Materials, 2015
Infection is the primary failure modality for transcutaneous implants because the skin breach provides a route for pathogens to enter the body. Intraosseous transcutaneous amputation prostheses (ITAP) are being developed to overcome this problem by ...
CJ Pendegrass, HT Lancashire, C Fontaine, G Chan, P Hosseini, GW Blunn   +5 more
doaj  

Inhalation of Low Molecular Weight Heparins as Prophylaxis against SARS-CoV-2

mBio, 2022
New SARS-CoV-2 variants of concern and waning immunity demonstrate the need for a quick and simple prophylactic agent to prevent infection. Low molecular weight heparins (LMWH) are potent inhibitors of SARS-CoV-2 binding and infection in vitro.
Julia Eder, Marta Bermejo-Jambrina, Killian E. Vlaming, Tanja M. Kaptein, Viktoria Zaderer, E. Marleen Kemper, Doris Wilflingseder, Sietze Reitsma, Godelieve J. de Bree, Danny M. Cohn, Teunis B. H. Geijtenbeek   +10 more
doaj   +1 more source

Challenges of Soft Tissue Integration Around Dental Implants and Strategies Based on Material Surface Modification

Advanced Materials Interfaces
The stability and long‐term survival of dental implants depend not only on osseointegration, but also on complete and rigid soft tissue integration (STI) in the transgingival area.
Shasha Jia, Hanqing Zhao, Yingliang Song, Yong Sun, Guowei Wang, Xiaojing Wang   +5 more
doaj   +1 more source

Uterine epithelial Gp130 orchestrates hormone response and epithelial remodeling for successful embryo attachment in mice

Scientific Reports, 2023
Leukemia inhibitory factor (LIF) receptor, an interleukin 6 cytokine family signal transducer (Il6st, also known as Gp130) that is expressed in the uterine epithelium and stroma, has been recognized to play an essential role in embryo implantation ...
Takafumi Namiki, Jumpei Terakawa, Harumi Karakama, Michiko Noguchi, Hironobu Murakami, Yoshinori Hasegawa, Osamu Ohara, Takiko Daikoku, Junya Ito, Naomi Kashiwazaki   +9 more
doaj   +1 more source

Attachment of Enterohemorrhagic Escherichia coli to Host Cells Reduces O Antigen Chain Length at the Infection Site That Promotes Infection

mBio, 2021
Many enteropathogenic bacteria express a needle-like type III secretion system (T3SS) that translocates effectors into host cells promoting infection.
Bin Liu, Chengqian Qian, Pan Wu, Xiaodan Li, Yutao Liu, Huiqian Mu, Min Huang, Yang Zhang, Tianyuan Jia, Yuanyuan Wang, Lu Wang, Xiao Zhang, Di Huang, Bin Yang, Lu Feng, Lei Wang   +15 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source