Results 141 to 150 of about 2,478,278 (345)

“Candida Albicans Interactions With The Host: Crossing The Intestinal Epithelial Barrier”

Tissue Barriers, 2019
Formerly a commensal organism of the mucosal surfaces of most healthy individuals, Candida albicans is an opportunistic pathogen that causes infections ranging from superficial to the more life-threatening disseminated infections, especially in the ever ...
L. Basmaciyan, F. Bon, Tracy Paradis, Pierre Lapaquette, F. Dalle   +4 more
semanticscholar   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Butyrate reduces epithelial barrier dysfunction induced by the foodborne mycotoxin deoxynivalenol in cell monolayers derived from pig jejunum organoids

Gut Microbes
The foodborne mycotoxin deoxynivalenol (DON) produced by Fusarium species threats animal and human health through disruption of the intestinal barrier.
Julie Alberge, Eloïse Mussard, Carine Al-Ayoubi, Corinne Lencina, Christelle Marrauld, Laurent Cauquil, Caroline S. Achard, Ivan Mateos, Imourana Alassane-Kpembi, Isabelle P. Oswald, Laura Soler, Sylvie Combes, Martin Beaumont   +12 more
doaj   +1 more source

Extracellular heat shock protein 90α mediates HDM-induced bronchial epithelial barrier dysfunction by activating RhoA/MLC signaling

Respiratory Research, 2017
Background The disruption and hyperpermeability of bronchial epithelial barrier are closely related to the pathogenesis of asthma. House dust mite (HDM), one of the most important allergens, could increase the airway epithelial permeability.
Hang-ming Dong, Yan-qing Le, Yan-hong Wang, Hai-jin Zhao, Chao-wen Huang, Ya-hui Hu, Li-shan Luo, Xuan Wan, Yi-lan Wei, Zi-qiang Chu, Wei Li, Shao-xi Cai   +11 more
doaj   +1 more source

Diesel exhaust and house dust mite allergen lead to common changes in the airway methylome and hydroxymethylome. [PDF]

, 2018
Exposures to diesel exhaust particles (DEP) from traffic and house dust mite (HDM) allergens significantly increase risks of airway diseases, including asthma. This negative impact of DEP and HDM may in part be mediated by epigenetic mechanisms.
Baccarelli, Andrea, Brandt, Eric B, Burleson, JD, Chen, Xiaoting, Ji, Hong, Weirauch, Matthew T, Zhang, Xiang, Zhang, Xue   +7 more
core  

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

Advanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li, Yifan Pan, Chikahiro Imashiro, Chaolun Xu, Jianxian He, Jingao Xu, Kewei Song, Ze Zhang, Chen Gao, Junbo Jiang, Runhuai Yang, Kayo Hirose, Shinjiro Umezu   +12 more
wiley   +1 more source

A Biologically‐Architected Wear and Damage‐Resistant Nanoparticle Coating From the Radular Teeth of Cryptochiton stelleri

Advanced Functional Materials, EarlyView.
The ultrahard teeth of mollusks that feed on rocky substrates contain a wear‐resistant coating on their surfaces consisting of densely packed mesocrystalline magnetic nanoparticles within an organic matrix. These coatings display significant hardness and toughness through their highly controlled mesocrystalline architectures.
Taifeng Wang, Yu Chen, Ezra Sarmiento, Taige Hao, Atsushi Arakaki, Michiko Nemoto, Pablo Zavattieri, David Kisailus   +7 more
wiley   +1 more source

S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function

Respiratory Research
Background Pulmonary fibrosis (PF) is a chronic and progressive respiratory disease characterized by the destruction of the alveolar–capillary barrier.
Mengyao Hao, Guodong Tang, Enjia Zhou, Rong Fu, MingJin Wang, Huimin Jiang, Xiaoguang Chen, Liping Bai, Xiaoxi Lv, Jing Jin   +9 more
doaj   +1 more source

Gingival epithelial barrier: regulation by beneficial and harmful microbes

Tissue Barriers, 2019
The gingival epithelium acts as a physical barrier to separate the biofilm from the gingival tissue, providing the first line of defense against bacterial invasion in periodontal disease.
N. Takahashi, B. Sulijaya, Miki Yamada-Hara, Takahiro Tsuzuno, K. Tabeta, K. Yamazaki   +5 more
semanticscholar   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source