Results 251 to 260 of about 274,446 (288)

Defective epithelial barrier function in asthma

Journal of Allergy and Clinical Immunology, 2011
Asthma is a complex disease involving gene and environment interactions. Although atopy is a strong predisposing risk factor for asthma, local tissue susceptibilities are required for disease expression. The bronchial epithelium forms the interface with the external environment and is pivotally involved in controlling tissue homeostasis through ...
Xiao C, Puddicombe SM, Field S, Haywood J, Broughton Head V, PUXEDDU, ILARIA, Haitchi HM, Vernon Wilson E, Sammut D, Bedke N, Cremin C, Sones J, Djukanović R, Howarth PH, Collins JE, Holgate ST, Monk P, Davies DE   +17 more
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Water permeability in different epithelial barriers

Biology of the Cell, 1989
The water permeability properties of a series of epithelial barriers (the toad urinary bladder [TUB], the rat caecum [RC], the distal human colon [DHC], and the human amnion [HA] were studied in different experimental conditions. Three parameters were simultaneously determined: the water permeability coefficient in the presence of a transepithelial ...
C, Capurro, E, Escobar, C, Ibarra, M, Porta, M, Parisi   +4 more
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Regulation of the intestinal epithelial paracellular barrier

Pharmaceutical Science & Technology Today, 1999
Paracellular transport of orally-administered drugs, the passage of molecules between adjacent intestinal epithelial cells, is impeded by a range of structural and functional features found in the intestine. An increased knowledge of the mechanisms that govern the paracellular barrier will enable the pharmaceutical scientist to design novel and ...
, Daugherty, , Mrsny
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Epithelial barrier and oral bacterial infection

Periodontology 2000, 2015
AbstractThe oral epithelial barrier separates the host from the environment and provides the first line of defense against pathogens, exogenous substances and mechanical stress. It consists of underlying connective tissue and a stratified keratinized epithelium with a basement membrane, whose cells undergo terminal differentiation resulting in the ...
Sabine E, Groeger, Joerg, Meyle
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The Alveolar Epithelial Barrier

1992
The primary purpose of this chapter is to briefly review the results of both experimental and clinical studies that have been completed in the last decade and provide new insights into the role of the alveolar epithelial barrier in the resolution of both hydrostatic and increased permeability pulmonary edema.
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Epithelial Barriers, Microbiota, and Colorectal Cancer

New England Journal of Medicine, 2013
There is an established link between the inflammation process and the genesis of colorectal cancer. A recent study suggests that intestinal microbiota may have a mediatory role between the initial steps of tumorigenesis and the initiation of an immune response that influences clinical outcome.
Awen M, Gallimore, Andrew, Godkin
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[The corneal epithelial barrier].

Oftalmologia (Bucharest, Romania : 1990), 1994
The corneal epithelium is an stratificated pavimentous epithelium. The epithelial cells are grouped in 3 levels: superficial cells, intermediate cells, basal cells. The superficial cells are solidarised by there type of junctional complexes: desmosomes, impermeable junctions, and communicating junctions.
S, Apostol, B, Cârstocea
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Epithelial Barrier Function and Immunity in Asthma

Annals of the American Thoracic Society, 2014
Abstract The bronchial epithelium is constantly exposed to a wide range of environmental materials present in inhaled air, including noxious gases and anthropogenic and natural particulates, such as gas and particles from car emissions, tobacco smoke, pollens, animal dander, and pathogens.
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Epithelial barrier homeostasis

Trends in Cell Biology
Epithelia cover the body's surface to form a barrier that segregates the internal body from the external environment. Tight junctions (TJs) seal the paracellular space and are crucial for the formation of the epithelial barrier. Epithelial barrier integrity is challenged by mechanical stress, infection, genetic lesions, or inflammation, and epithelial ...
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Analysis of Epithelial Barrier Integrity in Polarized Lung Epithelial Cells

2011
Epithelial surfaces of the body are a key component of host defense by providing a mechanical barrier against potentially harmful substances. The respiratory tract is constantly challenged by a wide range of airborne pathogens and particulates, and provides not only a mucosal barrier, but also an intricate innate immune defense system.
Monika, Strengert, Ulla G, Knaus
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