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Intestinal epithelial barrier functions in ageing
Ageing Research Reviews, 2019The intestinal epithelial barrier protects the mucosa of the gastrointestinal (GI)-tract and plays a key role in maintaining the host homeostasis. It encompasses several elements that include the intestinal epithelium and biochemical and immunological products, such as the mucus layer, antimicrobial peptides (AMPs) and secretory immunologlobulin A ...
Jacopo J V, Branca +2 more
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Epithelial Barriers in Homeostasis and Disease
Annual Review of Pathology: Mechanisms of Disease, 2010Epithelia form barriers that are essential to life. This is particularly true in the intestine, where the epithelial barrier supports nutrient and water transport while preventing microbial contamination of the interstitial tissues. Along with plasma membranes, the intercellular tight junction is the primary cellular determinant of epithelial barrier ...
Amanda M, Marchiando +2 more
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Water permeability in different epithelial barriers
Biology of the Cell, 1989The water permeability properties of a series of epithelial barriers (the toad urinary bladder [TUB], the rat caecum [RC], the distal human colon [DHC], and the human amnion [HA] were studied in different experimental conditions. Three parameters were simultaneously determined: the water permeability coefficient in the presence of a transepithelial ...
C, Capurro +4 more
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Epithelial barrier and oral bacterial infection
Periodontology 2000, 2015AbstractThe oral epithelial barrier separates the host from the environment and provides the first line of defense against pathogens, exogenous substances and mechanical stress. It consists of underlying connective tissue and a stratified keratinized epithelium with a basement membrane, whose cells undergo terminal differentiation resulting in the ...
Sabine E, Groeger, Joerg, Meyle
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Lymphostatin regulates epithelial barrier function
The FASEB Journal, 2007Lymphocyte inhibitory factor A ( lifA ) encodes for lymphostatin from Citrobacter rodentium and is responsible for colonization of extra‐intestinal organs.
Jan‐Michael Axel Klapproth +3 more
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[The corneal epithelial barrier].
Oftalmologia (Bucharest, Romania : 1990), 1994The corneal epithelium is an stratificated pavimentous epithelium. The epithelial cells are grouped in 3 levels: superficial cells, intermediate cells, basal cells. The superficial cells are solidarised by there type of junctional complexes: desmosomes, impermeable junctions, and communicating junctions.
S, Apostol, B, Cârstocea
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The Alveolar Epithelial Barrier
1992The primary purpose of this chapter is to briefly review the results of both experimental and clinical studies that have been completed in the last decade and provide new insights into the role of the alveolar epithelial barrier in the resolution of both hydrostatic and increased permeability pulmonary edema.
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Analysis of Epithelial Barrier Integrity in Polarized Lung Epithelial Cells
2011Epithelial surfaces of the body are a key component of host defense by providing a mechanical barrier against potentially harmful substances. The respiratory tract is constantly challenged by a wide range of airborne pathogens and particulates, and provides not only a mucosal barrier, but also an intricate innate immune defense system.
Monika, Strengert, Ulla G, Knaus
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Probiotic bacteria and intestinal epithelial barrier function
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2010The intestinal tract is a diverse microenvironment where more than 500 species of bacteria thrive. A single layer of epithelium is all that separates these commensal microorganisms and pathogens from the underlying immune cells, and thus epithelial barrier function is a key component in the arsenal of defense mechanisms required to prevent infection ...
Christina L, Ohland +1 more
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Protein transport across the lung epithelial barrier
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2003Alveolar lining fluid normally contains proteins of important physiological, antioxidant, and mucosal defense functions [such as albumin, immunoglobulin G (IgG), secretory IgA, transferrin, and ceruloplasmin]. Because concentrations of plasma proteins in alveolar fluid can increase in injured lungs (such as with permeability edema and inflammation ...
Kwang-Jin, Kim, Asrar B, Malik
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