Results 311 to 320 of about 2,478,278 (345)

Chenodeoxycholic acid (CDCA) protects against the LPS-induced impairment of intestinal epithelial barrier function via FXR-MLCK pathway.

Journal of Agricultural and Food Chemistry, 2019
Chenodeoxycholic acid (CDCA), a primary bile acid, has been demonstrated to play important roles as signaling molecule in various physiology functions. However, the role of CDCA in regulating intestinal barrier function remains largely unknown.
Min Song, Jiayi Ye, Fenglin Zhang, Han Su, Xiaohua Yang, Haiwen He, Fangfang Liu, Xiaotong Zhu, Lina Wang, P. Gao, G. Shu, Q. Jiang, Songbo Wang   +12 more
semanticscholar   +1 more source

Globale Umweltveränderungen und die „epithelial barrier hypothesis“

Die Dermatologie
Hintergrund: Die globale Belastung mit „non-communicable diseases“ (NCDs) hat in den letzten Jahrzehnten stark zugenommen, beeinflusst durch Umweltfaktoren. Für eine Reihe von Erkrankungen wurde eine Assoziation mit einer Schädigung epithelialer Grenzschichten gezeigt.Ziel: Es wird eine Übersicht über die gesundheitlichen Auswirkungen ...
Engelbert, N., Rohayem, R., Traidl-Hoffmann, C.   +2 more
openaire   +3 more sources

Disrupted Barrier Function through Epithelial Cell Apoptosis

Annals of the New York Academy of Sciences, 2006
Abstract:  Epithelial barrier function is determined by trans‐ and paracellular permeabilities, the latter of which is mainly influenced by tight junctions (TJs) and apoptotic leaks within the epithelium. The present article aims to present experimental evidence for a functional role of epithelial apoptoses by means of cell culture models as well as ...
Joerg-Dieter, Schulzke, Christian, Bojarski, Sebastian, Zeissig, Frank, Heller, Alfred H, Gitter, Michael, Fromm   +5 more
openaire   +2 more sources

Corneal Epithelial Barrier Function in Diabetic Patients

Cornea, 2004
To evaluate the corneal epithelial barrier function in diabetic patients.In 29 eyes of 29 diabetic patients and 55 eyes of 55 nondiabetic controls, corneal epithelial permeability to fluorescein was measured using an anterior fluorophotometer. The average fluorescein concentration in the central cornea was compared between diabetic patients and ...
Mamomu, Gekka, Kazunori, Miyata, Yuji, Nagai, Shingo, Nemoto, Tomokazu, Sameshima, Tatsuro, Tanabe, Shinji, Maruoka, Masaaki, Nakahara, Satoshi, Kato, Shiro, Amano   +9 more
openaire   +2 more sources

ALVEOLAR EPITHELIAL BARRIER

Clinics in Chest Medicine, 2000
Michael A. Matthay, Norimasa Fukuda, James Frank, Richard Kallet, Brian Daniel, Tsutomu Sakuma   +5 more
openaire   +1 more source

Breaking through the epithelial barrier

Science, 2014
Toxin Mechanism Botulinum neurotoxin (BoNT) poisons its host when it crosses the intestinal epithelial barrier. To help it cross this barrier, the toxin forms a large complex with three bacterial proteins called hemagglutinins (HAs). To find out what happens when this complex binds to a cell-adhesion protein called E-cadherin, Lee et al.
openaire   +1 more source

The blood–tumour barrier in cancer biology and therapy

Nature Reviews Clinical Oncology, 2021
Patricia S Steeg
exaly  

Epithelial Barrier Function

2020
Nan Wu, Howard Chi Ho Yim, Michael Grimm, Emad El-Omar   +3 more
openaire   +1 more source

Corneal Epithelial Barrier Function

Optometry - Journal of the American Optometric Association, 2005
Robert A. Ryan, Andrew S. Gurwood
openaire   +1 more source

Seminiferous Epithelial Barrier

2021
openaire   +1 more source