Results 141 to 150 of about 127,439 (263)

Quantitative Detection of Entotic Cell‐In‐Cell Structures Using Deformable Segmentation and Deep Learning

Cytometry Part A, EarlyView.
ABSTRACT Cell‐in‐cell (CIC) structures are among the most intriguing cellular phenomena occasionally observed in human cancer specimens. Once regarded as incidental findings, accumulating evidence has linked specific CIC subtypes, particularly entosis, to tumor progression and patient prognosis.
Maria V. Leyba‐Mesa, Mikołaj Biegański, Elijah Ray, Izabela Młynarczuk‐Bialy, Buket D. Barkana   +4 more
wiley   +1 more source

CLDN-2 Expression Aligns with Invasion-Associated Epithelial Remodeling in Colorectal Cancer. [PDF]

Cancers (Basel)
Markowski AR, Sadowska AJ, Mantiuk K, Romańczyk W, Pryczynicz A, Guzińska-Ustymowicz K.   +5 more
europepmc   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

TRPV4-Dependent Epithelial Mechanoadaptation and Barrier Remodeling Mediate Sennoside-Induced Distal Colonic Motility. [PDF]

Int J Mol Sci
Hara Y, Kawashima R, Tamaki S, Maekawa T, Kawamura YI, Tsujimoto T, Kusano C, Ichikawa T.   +7 more
europepmc   +1 more source

Cadherins and the Morphogenesis of Epithelial Tissues in Xenopus Embryos

Cold Spring Harbor Symposia on Quantitative Biology, 1992
openaire   +2 more sources

Biophysical processes of morphogenesis in lizard lungs

Developmental Dynamics, EarlyView.
Abstract Background The lungs of squamate reptiles (lizards and snakes) are highly diverse, exhibiting single chambers, multiple chambers, transitional forms with two to three chambers, along with a suite of other anatomical features, including finger‐like epithelial projections into the body cavity known as diverticulae.
Kaleb Hill, Aaron H. Griffing, Michael A. Palmer, Bezia Lemma, Aria S. Lupo, Tony Gamble, Natalia A. Shylo, Andrej Košmrlj, Paul A. Trainor, Celeste M. Nelson   +9 more
wiley   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

JNK inhibitor SP600125 alleviates TGF-β2-induced epithelial-mesenchymal transition in RPE cell <i>via</i> TGF-βR2/Smad2/3 and JNK/c-Jun pathway. [PDF]

Int J Ophthalmol
Zhang HH, Zhu YS, Guo JY, Chen XD.
europepmc   +1 more source

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

Equine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé, Jonathan Elliott, Nicola J. Menzies‐Gow, Simon R. Bailey, Nicholas J. Bamford, Yu‐Mei Chang, Matthew C. Gage   +6 more
wiley   +1 more source