Results 231 to 240 of about 127,439 (263)

Differential expression of neural‐cadherin in pulmonary epithelial tumours

Histopathology, 2008
Aims:  Neural (N)‐cadherin belongs to a group of transmembrane molecules with a crucial role in tissue morphogenesis and maintenance of an epithelioid phenotype and increased N‐cadherin expression is implicated in tumour progression and dedifferentiation.
D L, Zynger, N D, Dimov, L C, Ho, W B, Laskin, A V, Yeldandi   +4 more
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Epithelial Cell Shape: Cadherins and Small GTPases

Experimental Cell Research, 2000
Cadherins are cell-cell adhesion receptors that are essential for the establishment of the epithelial cell shape and maintenance of the differentiated epithelial phenotype. In order to show efficient adhesion, cadherin receptors require an association with actin filaments and the activity of RHO proteins.
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Expression of cadherins and alpha-catenin in primary epithelial tumors of the liver

Gastroenterology, 1996
Cadherins and their associated molecules, such as alpha-catenin, have been shown recently to play a pivotal role in epithelial carcinogenesis.The expression of E-cadherin, N-cadherin, and alpha-catenin in 10 normal samples, 28 focal nodular hyperplasias, 9 liver cell adenomas, 65 hepatocellular carcinomas, and 9 cholangiocarcinomas was studied by ...
Kozyraki R., Scoazec J. -Y., Flejou J. -F., D'Errico A., Bedossa P., Terris B., Fiorentino M., Bringuier A. -F., Grigioni W. F., Feldmann G.   +9 more
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E-cadherin expression in the epithelial components of mammary phyllodes tumors

Human Pathology, 2012
Phyllodes tumors are rare but clinically important fibroepithelial tumors of the breast. Both epithelial and stromal components actively interact with each other to participate in phyllodes tumor development. Accumulated evidence suggests that the Wnt signaling pathway is important in this stromal-epithelial interaction.
T C Putti, Rooshdiya Z Karim, Richard A Scolyer   +2 more
exaly   +4 more sources

Is the gastric epithelial barrier regulated by cadherin recruitment?

European Journal of Gastroenterology & Hepatology, 2002
While still highly controversial, regulation of junctional structure remains an important feature in many physiological/pathological conditions. Mizuno et al. here report a mechanism in stomach epithelia where additional copies of cadherins appear to be recruited to the cell surface, apparently to maintain the solute barrier.
J Steven, Alexander, Makoto, Sasaki
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Expression of P‐cadherin distinct from that of E‐cadherin in re‐epithelialization in neonatal rat skin

Development, Growth & Differentiation, 2005
Our previous study showed that an open wound made in neonatal rat skin was covered by migration of certain undifferentiated populations of keratinocytes as a multilayered cell sheet. In this study, the expression of the components of adherens junctions (AJ), E‐ and P‐cadherins, and beta‐catenin, was examined to understand the underlying mechanisms ...
Michiko, Koizumi, Takashi, Matsuzaki, Setsunosuke, Ihara   +2 more
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Brg1 inhibits E-cadherin expression in lung epithelial cells and disrupts epithelial integrity

Journal of Molecular Medicine, 2017
Brahma-related gene-1 (Brg1), a key chromatin remodeling factor, is associated with cell proliferation and migration in kidney and heart cells, but few reports have examined its role in airway epithelial cell. Airway epithelial injury, which is involved in the entire pathological process of asthma, is an important cause of recurrent asthma.
Ting, Wang, Wenjing, Zou, Chao, Niu, Fengxia, Ding, Yaping, Wang, Shuang, Cai, Hua, Zhu, Daiyin, Tian, Jihong, Dai, Enmei, Liu, Qing, Lu, Zhou, Fu, Lin, Zou   +12 more
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Epithelial E- and P-cadherins: Role and clinical significance in cancer

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012
E-cadherin and P-cadherin are major contributors to cell-cell adhesion in epithelial tissues, playing pivotal roles in important morphogenetic and differentiation processes during development, and in maintaining integrity and homeostasis in adult tissues.
Joana, Paredes, Joana, Figueiredo, André, Albergaria, Patrícia, Oliveira, Joana, Carvalho, Ana Sofia, Ribeiro, Joana, Caldeira, Angela Margarida, Costa, Joana, Simões-Correia, Maria José, Oliveira, Hugo, Pinheiro, Salomé S, Pinho, Rita, Mateus, Celso A, Reis, Marina, Leite, Maria Sofia, Fernandes, Fernando, Schmitt, Fátima, Carneiro, Céu, Figueiredo, Carla, Oliveira, Raquel, Seruca   +20 more
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Cadherin-dependent organization and disorganization of epithelial architecture.

Princess Takamatsu symposia, 1997
Epithelial cell layers exhibit an ordered polarized architecture. However, such structures are disrupted during malignant transformation, which generally coincides with a loss of regulate cell growth. We are investigating how the cadherin cell adhesion system controls these processes.
M, Takeichi, M, Watabe, S, Shibamoto, F, Ito   +3 more
openaire   +1 more source

Cadherin Function in Bronchial Epithelial Wound Healing [PDF]

, 2001
The bronchial epithelial lining is often impaired in asthma with observed epithelial denudation. Normal epithelium is scaffolded by various adhesion molecules which interact and co-exist in such a fashion that together they support an epithelium that functions to line the airway lumen forming a selectivity permeable barrier, protecting the underlying ...
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