Results 211 to 220 of about 127,702 (262)

Jaboticaba peel extract limits castration-resistant prostate cancer aggressiveness by counteracting EMT through steroid hormone and TGF-β signaling modulation. [PDF]

J Mol Histol
Schievano FR, de Souza Gianchetto J, Santos FR, Maróstica Júnior MR, Cagnon VHA, Montico F.   +5 more
europepmc   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

Hepatocyte growth factor blocks epithelial-mesenchymal transition and fibrosis of ureteral epithelial cells in UPJO. [PDF]

BMC Pediatr
Lin X, Wang Y, Jian Z, Yang F, Lin S, Huang W, Yang Y, Chen S, Chen J, Chen W.   +9 more
europepmc   +1 more source

Postcode‐Level Variation and Environmental Determinants of Respiratory Allergies in a Large German Cohort

Allergy, EarlyView.
Young children (0–9 years) and residents of urban areas appeared particularly vulnerable to respiratory allergy development and exacerbation. Incidence showed nonlinear associations with PM10, PM2.5, temperature, and alder/birch pollen, while DPMR showed similar patterns, except for NO2 and the interaction O3*NO2.
Trang Dao‐Siebel, Christoph Knote, Christoph Müller, Thilo Erbertseder, Elke Hertig, Roxana Halbleib, Evelyn Lamy   +6 more
wiley   +1 more source

Exploring the Role of <i>Pseudomonas aeruginosa</i> Elastase in Lung Epithelial Barrier Dysfunction: Advancing toward Antivirulence Therapies. [PDF]

ACS Infect Dis
Shafiei R, Alhayek A, Hiller L, Latta L, Neu T, Aljohmani A, Abdollahibiroun S, Schönborn EM, Yildiz D, Schneider-Daum N, Lehr CM, Haupenthal J, Hirsch AKH.   +12 more
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Epigenetic alterations in cancer metastasis: molecular mechanisms and implications for precision oncology. [PDF]

Front Oncol
Turna S, Demokan S.
europepmc   +1 more source

LAMC2 Drives Airway Remodeling in COPD via EMT Regulation Through the AKT Pathway. [PDF]

Int J Chron Obstruct Pulmon Dis
Wang Z, Shi J, Zhang Y, Luo Y, Rao Y, Qu J, Gai X, Sun Y.   +7 more
europepmc   +1 more source

Sulforaphane Enhances Cytotoxic Effects of Non-Thermal Plasma and Tirapazamine Combination Therapy in Pancreatic Adenocarcinoma Cells. [PDF]

Cells
Shaan I, Gulledge B, Poplavskyi M, Eubank M, Domukhovska A, Weinrieb A, Alseid D, Prentice I, Rosen S, Rayan G, Zucker SN.   +10 more
europepmc   +1 more source

The protease code of the bacterial gut microbiota: ecological regulation, barrier disruption, and rewiring host defense and signaling. [PDF]

Gut Microbes
Eckhard U, Ramírez-Larrota JS, Estevan-Morió E, Gomis-Rüth FX.   +3 more
europepmc   +1 more source