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Intestinal epithelial dysplasia (tufting enteropathy) [PDF]

Orphanet Journal of Rare Diseases, 2007
Intestinal epithelial dysplasia (IED), also known as tufting enteropathy, is a congenital enteropathy presenting with early-onset severe intractable diarrhea causing sometimes irreversible intestinal failure. To date, no epidemiological data are available, however, the prevalence can be estimated at around 1/50,000-100,000 live births in Western Europe.
de Serres Natacha, Ruemmele Frank, Salomon Julie, Goulet Olivier, Brousse Nicole   +4 more
openaire   +3 more sources

Morphometric analysis of suprabasal cell layer in oral epithelial dysplasia: A computer-assisted microscopic study

Journal of Pharmacy and Bioallied Sciences, 2020
Background: Oral leukoplakia is the most common precancerous lesion. Various grading systems based on histological findings have been proposed for dysplasia.
Viswanathan Prema, Thomson Thomas, Prasad Harikrishnan, Mani Viswanathan, Kenniyan Kumar Srichinthu, Krishnan Rajkumar   +5 more
doaj   +1 more source

Intestinal epithelial dysplasia

Pacific Medical Journal, 2020
The article presents a clinical case of intestinal epithelial dysplasia (tufting enteropathy), a rare disease which relates to congenital diarrheas, has a particular clinical presentation and is life-threating. The diagnosis was confirmed by histological examination and electronic microscopy of mucous membrane of small intestine. Additional evidence is
T. E. Taranushenko, E. M. Vasilyeva, E. V. Antsiferova, L. N. Karpova, Y. S. Shamova   +4 more
openaire   +2 more sources

Expression of Ki-67, p53, α-SMA and COX-2 in lichen planus and related lesions: A pilot study

Journal of Oral Biology and Craniofacial Research, 2019
Background: Researchers have struggled to understand the natural history of lesions presenting with both lichenoid features and epithelial dysplasia.
D.S. Sanketh, Karuna Kumari, Roopa S. Rao, Vanishree C. Haragannavar, Sachin C. Sarode, Gargi S. Sarode, A. Thirumal Raj, Shankargouda Patil   +7 more
doaj   +1 more source

Comparison of expression of myofibroblasts in normal oral mucosa, oral epithelial dysplasia, and oral squamous cell carcinoma using α-SMA and vimentin: An immunohistochemical study

Journal of Family Medicine and Primary Care, 2020
Background: Myofibroblasts are thought to play critical roles in inflammation, growth, repair, premalignancy, and malignancy. This study was done to evaluate, compare and co- relate the progressive increase in the immunohistochemical expression of ...
Amani Mahajan, Andleeb Manhas, Tania Aneja, Swati Parhar, Priyanka Kumari, Anubhuti, Harkanwal P Singh   +6 more
doaj   +1 more source

Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia. [PDF]

PLoS ONE, 2016
Lysophosphatidic acid (LPA) acts on LPA2 receptor to mediate multiple pathological effects that are associated with tumorigenesis. The absence of LPA2 attenuates tumor progression in rodent models of colorectal cancer, but whether overexpression of LPA2 ...
Michihiro Yoshida, Peijian He, C Chris Yun   +2 more
doaj   +1 more source

Suprabasal expression of Ki-67 as a marker for the severity of oral epithelial dysplasia and oral squamous cell carcinoma

Contemporary Clinical Dentistry, 2013
Background: Transition of the normal oral epithelium to dysplasia and to malignancy is featured by increased cell proliferation. To evaluate the hypothesis of distributional disturbances in proliferating and stem cells in oral epithelial dysplasia and ...
Nidhi Dwivedi, Shaleen Chandra, Bina Kashyap, Vineet Raj, Akhil Agarwal   +4 more
doaj   +1 more source

Effect of tobacco, alcohol, and smoking habits in oral precancer with histological proven epithelial dysplasia

Journal of Oral Biology and Craniofacial Research, 2012
Objectives: To assess the effect of risk factors tobacco, alcohol, and smoking habits in oral precancer patients with epithelial dysplasia status. Material and methods: The study sample included biopsy proven cases of 29 oral submucous fibrosis (OSMF ...
Seema Nayak, Saumya Chandra, Divya Mehrotra, Sumit Kumar, S.P. Agrawal, Sandeep Kumar, Madhu Mati Goel   +6 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Assessment and comparison of p53 and p63 expression in oral epithelial dysplasia and squamous cell carcinoma

SRM Journal of Research in Dental Sciences, 2014
Aim: p53 and p63 are the important genes associated with oral cancer. The aim of this study was to evaluate and compare the immunohistochemical expression of p53 and p63 in oral epithelial dysplasia and squamous cell carcinoma (SCC).
Smitha Sammith Shetty, Rekha Krishnapillai, Sudeendra Prabhu   +2 more
doaj   +1 more source