Results 21 to 30 of about 94,075 (184)
bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice [PDF]
, 2015 Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibility
Abuderman, A A +5 more
core +2 more sources
Feasibility of recruitment to an oral dysplasia trial in the United Kingdom [PDF]
, 2012 Background: Oral epithelial dysplasia (OED) has a malignant potential. Therapeutic options for OED remain both limited and without good evidence. Despite surgery being the most common method of treating OED, recurrence and potentially significant ...
Dunn, Janet A. +3 more
core +2 more sources
Journal of Oral Biology and Craniofacial Research, 2012 Objectives: To assess the effect of risk factors tobacco, alcohol, and smoking habits in oral precancer patients with epithelial dysplasia status. Material and methods: The study sample included biopsy proven cases of 29 oral submucous fibrosis (OSMF ...
Seema Nayak +6 more
doaj +1 more source
SRM Journal of Research in Dental Sciences, 2014 Aim: p53 and p63 are the important genes associated with oral cancer. The aim of this study was to evaluate and compare the immunohistochemical expression of p53 and p63 in oral epithelial dysplasia and squamous cell carcinoma (SCC).
Smitha Sammith Shetty +2 more
doaj +1 more source
Psychosocial impacts of oral epithelial dysplasia
Journal of Oral Pathology & Medicine, 2021 Abstract Background The psychosocial impact of receiving the diagnosis of oral epithelial dysplasia, which presents up to 3.5% increased annual risk of mouth cancer, remains unknown. Using validated instruments, the present study aimed to investigate the prevalence and existing correlations ...
Abdullah Alsoghier +3 more
openaire +3 more sources
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. [PDF]
, 2013 Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), graft-versus-host disease (GVHD), and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are common human gastrointestinal diseases that share inflammation as a key
Bortner, James D +6 more
core +2 more sources
Dental Journal, 2019 Background: Cigarette smoke contains various carcinogenic substances such as polycyclic aromatic hydrocarbons and nitrosamines. These chemicals not only have the potential to damage DNA, but can also induce genetic mutations and activate genes that ...
Dorisna Prijaryanti +4 more
doaj +1 more source
Actinic keratoses show variable histological basal growth patterns - a proposed classification adjustment [PDF]
, 2017 Background: Common histological classification schemes of actinic keratoses (AK) do not evaluate growth patterns at basal epidermal aspects of AK. Until now, the importance of basal epidermal growth patterns of AK has not been studied. Objective: To
Dirschka, T. +6 more
core +1 more source
Expression of p63 in potentially malignant and malignant oral lesions
Journal of Oral Biology and Craniofacial Research, 2015 Background: p63, a member of p53 family, known to be expressed in embryonic tissues and basal regenerative layers of many epithelial tissues in the adult, is also expressed in various benign and malignant lesions of body including lesions of oral cavity.
Anju Sinha +5 more
doaj +1 more source
Histomorphometric Analysis of Angiogenesis using CD31 Immunomarker and Mast Cell Density in Oral Premalignant and Malignant Lesions: A Pilot Study [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Mast cells have been implicated in promoting angiogenesis in malignant tumors of lung, oesophagus and breast, but there are few studies on Oral Squamous Cell Carcinomas (OSCC).
M Jyothsna, M Rammanohar, Kiran Kumar
doaj +1 more source