Results 21 to 30 of about 56,527 (245)

Psychosocial impacts of oral epithelial dysplasia

Journal of Oral Pathology & Medicine, 2021
Abstract Background The psychosocial impact of receiving the diagnosis of oral epithelial dysplasia, which presents up to 3.5% increased annual risk of mouth cancer, remains unknown. Using validated instruments, the present study aimed to investigate the prevalence and existing correlations ...
Abdullah Alsoghier, Richeal Ni Riordain, Stefano Fedele, Stephen Porter   +3 more
openaire   +3 more sources

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

The correlation between exposure to cigarette smoke and the degree of mucosal epithelium-based dysplasia in Rattus norvegicus tongues

Dental Journal, 2019
Background: Cigarette smoke contains various carcinogenic substances such as polycyclic aromatic hydrocarbons and nitrosamines. These chemicals not only have the potential to damage DNA, but can also induce genetic mutations and activate genes that ...
Dorisna Prijaryanti, Diah Savitri Ernawati, Desiana Radithia, Hening Tuti Hendarti, Rosnah Binti Zain   +4 more
doaj   +1 more source

Expression of p63 in potentially malignant and malignant oral lesions

Journal of Oral Biology and Craniofacial Research, 2015
Background: p63, a member of p53 family, known to be expressed in embryonic tissues and basal regenerative layers of many epithelial tissues in the adult, is also expressed in various benign and malignant lesions of body including lesions of oral cavity.
Anju Sinha, Shaleen Chandra, Vineet Raj, Iram Zaidi, Shikha Saxena, Ruby Dwivedi   +5 more
doaj   +1 more source

Histomorphometric Analysis of Angiogenesis using CD31 Immunomarker and Mast Cell Density in Oral Premalignant and Malignant Lesions: A Pilot Study [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Mast cells have been implicated in promoting angiogenesis in malignant tumors of lung, oesophagus and breast, but there are few studies on Oral Squamous Cell Carcinomas (OSCC).
M Jyothsna, M Rammanohar, Kiran Kumar
doaj   +1 more source

Immunohistochemical evaluation of E-cadherin in oral epithelial dysplasia and squamous cell carcinoma

Indian Journal of Pathology and Microbiology, 2022
Aim: To evaluate the expression of E-cadherin (E-cad) in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Material and Method: Immunohistochemistry was used to detect E-cad expression in 20 cases each of normal oral mucosa, oral ...
Jaishree Sharma, Manish Bhargava, Shivani Aggarwal, Ashim Aggarwal, Anchal Varshney, Disha Chopra   +5 more
doaj   +1 more source

Etiology and pathogenesis of cervical intraepithelial neoplasia (review of foreign literature)

Медицинский совет, 2015
Cervical intraepithelial neoplasia (CIN) is atypical transformation of squamos epithelium without stromal invasion predictive of cervical cancer. According to the World Health Organization (2014), there is mild cervical epithelial neoplasia (CIN I; mild
S. A. Levakov, N. A. Sheshukova, L. S. Dabagyan   +2 more
doaj   +1 more source

Oral Epithelial Dysplasia and Premalignancy [PDF]

Head and Neck Pathology, 2019
Leukoplakia and erythroplakia are two entities under the moniker of "oral potentially malignant disorders" that are highly associated with the presence of oral epithelial dysplasia (OED) at first biopsy, while lesions of submucous fibrosis develop OED after being present for years.
openaire   +2 more sources

Association of Syndecan-1 immunoexpression with epithelial dysplasia in oral verrucous carcinoma

Bangabandhu Sheikh Mujib Medical University Journal
Background: Oral verrucous carcinoma (OVC) is an uncommon variant of well-differentiated squamous cell carcinoma with an excellent prognosis. Epithelial dysplasia in OVC is a sign of a poorer prognosis.
Md. Akhtaruzzaman, Bishnu Pada Dey, Israt Jahan, Md. Mahabub Alam, Sultana Gulshana Banu   +4 more
doaj   +1 more source

Epithelial dysplasia in Caroli's disease. [PDF]

Gut, 1989
We report a young patient with a solitary intrahepatic cyst without demonstrable connection with the biliary tree. The operative appearances suggested hydatid disease but histological examination of the resected cyst showed that it was the result of Caroli's disease already complicated by severe dysplasia.
J B, Fozard, J I, Wyatt, R I, Hall
openaire   +2 more sources