Results 1 to 10 of about 3,788,205 (194)

Progression-free survival and overall survival after BRCA1/2-associated epithelial ovarian cancer: A matched cohort study.

PLoS ONE, 2022
IntroductionGermline BRCA1/2-associated epithelial ovarian cancer has been associated with better progression-free survival and overall survival than sporadic epithelial ovarian cancer, but conclusive data are lacking.MethodsWe matched 389 BRCA1 ...
Bernadette A M Heemskerk-Gerritsen, Antoinette Hollestelle, Christi J van Asperen, Irma van den Beek, Willemien J van Driel, Klaartje van Engelen, Encarna B Gómez Garcia, Joanne A de Hullu, Marco J Koudijs, Marian J E Mourits, Maartje J Hooning, Ingrid A Boere   +11 more
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Factors Associated With Recurrence Of Epithelial Ovarian Cancer In RSUP Dr. Kariadi Semarang

Diponegoro International Medical Journal, 2022
Introductions: Epithelial ovarian cancer accounts for 90% of all ovarian malignancies. More than 70% of patients will experience a relapse even after receiving operative therapy and chemotherapy.
Isabela Marsialina Kurube, Ediwibowo Ambari, Teuku Mirza Iskandar, Hary Tjahjanto, Julian Dewantiningrum, Arufiadi Anityo Mochtar, Yuli Trisetiyono   +6 more
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Preoperative Platelet-Lymphocyte Ratio as a Prognostic Factor of Epithelial Ovarian Cancer

Indonesian Journal of Obstetrics and Gynecology, 2023
Objective: To determine whether platelet-lymphocyte ratio can be a prognostic factor for epithelial ovarian cancer. Methods: This study was a retrospective cohort with analytical design, conducted in the Department of Obstetrics and Gynecology of Prof ...
Johan Winata, Bismarck Joel Laihad, Frank Mitchell Marvel Wagey   +2 more
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Pentraxin 3 is a diagnostic and prognostic marker for ovarian epithelial cancer patients based on comprehensive bioinformatics and experiments

Cancer Cell International, 2021
Background Ovarian epithelial cancer is one of the leading malignant tumors in gynecology and lacks effective diagnostic and prognostic markers. Our study aims to screen and verify ovarian epithelial cancer biomarkers.
Xiaoying Chang, Dan Li, Chang Liu, Zhe Zhang, Tao Wang   +4 more
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ChIP-seq defined genome-wide map of TGFβ/SMAD4 targets: implications with clinical outcome of ovarian cancer. [PDF]

PLoS ONE, 2011
Deregulation of the transforming growth factor-β (TGFβ) signaling pathway in epithelial ovarian cancer has been reported, but the precise mechanism underlying disrupted TGFβ signaling in the disease remains unclear.
Brian A Kennedy, Daniel E Deatherage, Fei Gu, Binhua Tang, Michael W Y Chan, Kenneth P Nephew, Tim H-M Huang, Victor X Jin   +7 more
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Meta-analysis of the diagnostic value of 18F-FDG PET/CT in the recurrence of epithelial ovarian cancer

Frontiers in Oncology, 2022
BackgroundOvarian cancer is the leading cause of cancer-related death among gynecologic malignancies. With much evidence suggesting that 18F-FDG PET/CT may be an excellent imaging test for the diagnosis of epithelial ovarian cancer recurrence, we ...
Xiaoyan Wang, Lifeng Yang, Yan Wang
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Association of a common variant of gene with increased risk of serous epithelial ovarian cancer

Tumor Biology, 2017
In China, the majority of ovarian cancer patients (80%–90%) are women who are diagnosed with epithelial ovarian cancer. The SYNPO2 gene has recently been reported to be associated with epithelial ovarian cancer in Europeans.
Li Ma, Wei Zhang, Zhaoli Ding, Stephen G Wu, Yaofeng Jin, Na Jiang, Hongyan Du, Dongge Cai, Li Miao, Xiaoli Chen   +9 more
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Inflammatory Cytokine Tumor Necrosis Factor α Confers Precancerous Phenotype in an Organoid Model of Normal Human Ovarian Surface Epithelial Cells

Neoplasia: An International Journal for Oncology Research, 2009
In this study, we established an in vitro organoid model of normal human ovarian surface epithelial (HOSE) cells. The spheroids of these normal HOSE cells resembled epithelial inclusion cysts in human ovarian cortex, which are the cells of origin of ...
Joseph Kwong, Franky Leung Chan, Kwong-kwok Wong, Michael J. Birrer, Kyra M. Archibald, Frances R. Balkwill, Ross S. Berkowitz, Samuel C. Mok   +7 more
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Study on the expression of MMP-9 and NF-κB proteins in epithelial ovarian cancer tissue and their clinical value

BIO Web of Conferences, 2017
Objective: To investigate the expression of matrix metalloproteinase-9 (MMP-9) and nuclear factor κappa-B (NF-κB) in different ovarian tissue and explore the relationship between their expression and clinicopathological features of epithelial ovarian ...
Wei Shen, Juan Chen, Xiurong Li, Jie Yin
doaj   +1 more source

Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer

Mediators of Inflammation, 2016
Notch3 and pS6 play important roles in tumor angiogenesis. To assess the expression of Notch3 and pS6 in Chinese ovarian epithelial cancer patients, a ten-year follow-up study was performed in ovarian epithelial cancer tissues from 120 specimens of human
Zhaoxia Liu, Rongna Yun, Xiaolin Yu, Hui Hu, Genhua Huang, Buzhen Tan, Tingtao Chen   +6 more
doaj   +1 more source