Results 21 to 30 of about 182,825 (308)

Role of EZH2 in epithelial ovarian cancer: from biological insights to therapeutic target

open access: yesFrontiers in Oncology, 2013
EZH2 is the catalytic subunit of polycomb repressive complex 2 (PRC2), which generates a methylation epigenetic mark at lysine-27 residue of histone H3 (H3K27me3) to silence gene expression.
Hua eLi, Rugang eZhang
doaj   +1 more source

Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer

open access: yesMediators of Inflammation, 2016
Notch3 and pS6 play important roles in tumor angiogenesis. To assess the expression of Notch3 and pS6 in Chinese ovarian epithelial cancer patients, a ten-year follow-up study was performed in ovarian epithelial cancer tissues from 120 specimens of human
Zhaoxia Liu   +6 more
doaj   +1 more source

Altered Expression Pattern of Topoisomerase IIα, in Ovarian Tumor Epithelial and Stromal Cells after Platinum-Based Chemotherapy

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
OBJECTIVE: The aim of this study was to evaluate the expression of topoisomerase IIα (TOP2A) in epithelial and stromal cells of ovarian cancer. METHODS: TOP2A expression was analyzed in normal ovarian tissue and in laser-microdissected ovarian tumor ...
Radoslav Chekerov   +8 more
doaj   +1 more source

Deciphering tumor immune microenvironment differences between high-grade serous and endometrioid ovarian cancer to investigate their potential in indicating immunotherapy response

open access: yesJournal of Ovarian Research, 2023
Background Ovarian cancer is a significant public health concern with a poor prognosis for epithelial ovarian cancer. To explore the potential of immunotherapy in treating epithelial ovarian cancer, we investigated the immune microenvironments of 52 ...
Hua Yang   +8 more
doaj   +1 more source

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers [PDF]

open access: yes, 2011
Genetic variation at the TERT-CLPTM1L locus at 5p15.33 is associated with susceptibility to several cancers, including epithelial ovarian cancer (EOC). We have carried out fine-mapping of this region in EOC which implicates an association with a single
Chaiwerawattana, A   +339 more
core   +1 more source

Mass spectrometric profiling reveals association of -glycan patterns with epithelial ovarian cancer progression

open access: yesTumor Biology, 2017
Aberrant changes of N -glycan modifications on proteins have been linked to various diseases including different cancers, suggesting possible avenue for exploring their etiologies based on N -glycomic analysis.
Huanhuan Chen   +5 more
doaj   +1 more source

The Prevalence of Occult Omental Metastases in Patients with Epithelial Ovarian Cancer

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2018
Objective: Studies regarding omentectomy on epithelial ovarian cancer are scarce with conflicting results; this study is aimed to investigate the prevalence of occult metastases in patients with epithelial ovarian cancer of the omentum.
Hariyono Winarto, Ken Indra
doaj   +1 more source

IL-36α suppresses proliferation of ovarian cancer cells

open access: yesTumor Biology, 2017
Interleukin-36α (IL-36α), also formerly known as IL-1F6, is pertaining to IL-1 family members that has been shown to play an important pro-inflammatory role in chronic immune disorders.
Lei Chang, Ruixia Guo, Zhongfu Yuan
doaj   +1 more source

MiRNA-802 suppresses proliferation and migration of epithelial ovarian cancer cells by targeting YWHAZ

open access: yesJournal of Ovarian Research, 2019
Background The imbalance of expression of microRNA-802 may have a significant place in tumor progression. However, the bio-function of epithelial ovarian cancer cells remains unclear.
Bo Yang, Li Sun, Lei Liang
doaj   +1 more source

Functional polymorphisms in FOXC2 gene and Epithelial ovarian Cancer susceptibility in Chinese population

open access: yesJournal of Ovarian Research, 2020
Background Epithelial ovarian cancer (EOC) is highly lethal gynecological cancer. Forkhead Box Protein C2 (FOXC2) promotes occurrence and development of various malignant tumors.
Zhijiao Zhou   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy