Results 21 to 30 of about 3,788,205 (194)

Epithelial Ovarian Cancers and Endometriosis [PDF]

open access: yesGynecologic and Obstetric Investigation, 2015
<b><i>Aims:</i></b> To determine the prevalence of endometriosis in epithelial ovarian cancers (EOC) and the association among their histological subtypes and with endometrial carcinoma. <b><i>Methods:</i></b> An observational cohort study performed in 192 patients operated on for EOC, 30 women with ...
Acién, Pedro   +4 more
openaire   +3 more sources

The cyclin-dependent kinase inhibitor p57(Kip2) is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer [PDF]

open access: yes, 2012
Carboplatin remains a first-line agent in the management of epithelial ovarian cancer (EOC). Unfortunately, platinum-resistant disease ultimately occurs in most patients.
Madhuri, K   +17 more
core   +1 more source

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers [PDF]

open access: yes, 2011
Genetic variation at the TERT-CLPTM1L locus at 5p15.33 is associated with susceptibility to several cancers, including epithelial ovarian cancer (EOC). We have carried out fine-mapping of this region in EOC which implicates an association with a single
Chaiwerawattana, A   +339 more
core   +1 more source

The effects of anti-IL-6 therapy in advanced ovarian cancer [PDF]

open access: yes, 2010
PhDIL-6 is a pleiotropic cytokine that has a significant role in inflammatory processes. In relation to ovarian cancer biology there is emerging evidence that it mediates processes relating to tumour growth, invasion, angiogenesis and chemo-resistance ...
Coward, Jermaine
core   +4 more sources

Incomplete pregnancy and risk of ovarian cancer: Results from two Australian case–control studies and systematic review [PDF]

open access: yes, 2009
Although full-term pregnancies reduce the risk of ovarian cancer, it has not been conclusively established whether incomplete pregnancies also influence risk.
Dick, Marie-Louise B.   +12 more
core   +1 more source

Role of EZH2 in epithelial ovarian cancer: from biological insights to therapeutic target

open access: yesFrontiers in Oncology, 2013
EZH2 is the catalytic subunit of polycomb repressive complex 2 (PRC2), which generates a methylation epigenetic mark at lysine-27 residue of histone H3 (H3K27me3) to silence gene expression.
Hua eLi, Rugang eZhang
doaj   +1 more source

Mass spectrometric profiling reveals association of -glycan patterns with epithelial ovarian cancer progression

open access: yesTumor Biology, 2017
Aberrant changes of N -glycan modifications on proteins have been linked to various diseases including different cancers, suggesting possible avenue for exploring their etiologies based on N -glycomic analysis.
Huanhuan Chen   +5 more
doaj   +1 more source

Advances in epithelial ovarian cancer

open access: yesAustralian Journal of General Practice, 2020
Most epithelial ovarian cancer occurs in older women, with a mean age at diagnosis of 62 years and an overall five‑year survival rate in Australia of 43%. Most women are diagnosed with advanced disease of high-grade serous type with 20-30% five-year survival; 70% relapse within three years of initial treatment.
Deborah, Neesham   +2 more
openaire   +3 more sources

Altered Expression Pattern of Topoisomerase IIα, in Ovarian Tumor Epithelial and Stromal Cells after Platinum-Based Chemotherapy

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
OBJECTIVE: The aim of this study was to evaluate the expression of topoisomerase IIα (TOP2A) in epithelial and stromal cells of ovarian cancer. METHODS: TOP2A expression was analyzed in normal ovarian tissue and in laser-microdissected ovarian tumor ...
Radoslav Chekerov   +8 more
doaj   +1 more source

Deciphering tumor immune microenvironment differences between high-grade serous and endometrioid ovarian cancer to investigate their potential in indicating immunotherapy response

open access: yesJournal of Ovarian Research, 2023
Background Ovarian cancer is a significant public health concern with a poor prognosis for epithelial ovarian cancer. To explore the potential of immunotherapy in treating epithelial ovarian cancer, we investigated the immune microenvironments of 52 ...
Hua Yang   +8 more
doaj   +1 more source

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