Results 21 to 30 of about 276,970 (298)

Deciphering tumor immune microenvironment differences between high-grade serous and endometrioid ovarian cancer to investigate their potential in indicating immunotherapy response

Journal of Ovarian Research, 2023
Background Ovarian cancer is a significant public health concern with a poor prognosis for epithelial ovarian cancer. To explore the potential of immunotherapy in treating epithelial ovarian cancer, we investigated the immune microenvironments of 52 ...
Hua Yang, Xiangyu Gu, Rong Fan, Qun Zhu, Sen Zhong, Xirun Wan, Qian Chen, Lan Zhu, Fengzhi Feng   +8 more
doaj   +1 more source

Mass spectrometric profiling reveals association of -glycan patterns with epithelial ovarian cancer progression

Tumor Biology, 2017
Aberrant changes of N -glycan modifications on proteins have been linked to various diseases including different cancers, suggesting possible avenue for exploring their etiologies based on N -glycomic analysis.
Huanhuan Chen, Zaian Deng, Chuncui Huang, Hongmei Wu, Xia Zhao, Yan Li   +5 more
doaj   +1 more source

The Prevalence of Occult Omental Metastases in Patients with Epithelial Ovarian Cancer

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective: Studies regarding omentectomy on epithelial ovarian cancer are scarce with conflicting results; this study is aimed to investigate the prevalence of occult metastases in patients with epithelial ovarian cancer of the omentum.
Hariyono Winarto, Ken Indra
doaj   +1 more source

HE4 in the differential diagnosis of ovarian masses [PDF]

, 2015
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela, ANGELONI, Antonio, Flavia Longo, MANGANARO, Lucia, PORPORA, Maria Grazia, Teresa Granato   +5 more
core   +1 more source

Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer

Mediators of Inflammation, 2016
Notch3 and pS6 play important roles in tumor angiogenesis. To assess the expression of Notch3 and pS6 in Chinese ovarian epithelial cancer patients, a ten-year follow-up study was performed in ovarian epithelial cancer tissues from 120 specimens of human
Zhaoxia Liu, Rongna Yun, Xiaolin Yu, Hui Hu, Genhua Huang, Buzhen Tan, Tingtao Chen   +6 more
doaj   +1 more source

Altered Expression Pattern of Topoisomerase IIα, in Ovarian Tumor Epithelial and Stromal Cells after Platinum-Based Chemotherapy

Neoplasia: An International Journal for Oncology Research, 2006
OBJECTIVE: The aim of this study was to evaluate the expression of topoisomerase IIα (TOP2A) in epithelial and stromal cells of ovarian cancer. METHODS: TOP2A expression was analyzed in normal ovarian tissue and in laser-microdissected ovarian tumor ...
Radoslav Chekerov, Irina Klaman, Menelaos Zafrakas, Dominique Könsgen, Alexander Mustea, Beate Petschke, Werner Lichtenegger, Jalid Sehouli, Edgar Dahl   +8 more
doaj   +1 more source

Functional polymorphisms in FOXC2 gene and Epithelial ovarian Cancer susceptibility in Chinese population

Journal of Ovarian Research, 2020
Background Epithelial ovarian cancer (EOC) is highly lethal gynecological cancer. Forkhead Box Protein C2 (FOXC2) promotes occurrence and development of various malignant tumors.
Zhijiao Zhou, Xiang Ou, Qiong Zou, Ling Chu, Xiyun Quan, Yong Chen, Yang Liu   +6 more
doaj   +1 more source

CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential [PDF]

, 2002
Although early stage ovarian cancer can be effectively treated with surgery and chemotherapy, the majority of cases present with advanced disease, which remains essentially incurable.
Auersperg, N. (N.), Birrer, M.J. (Michael J.), Choi, Y.H. (Yung-Hyun), Dayton, M. (M.), Dent, P. (P.), Gardner, G.J. (Ginger J.), Kinoshita, I. (Ichiro), Manzano, R.G. (Ramón G.), Montuenga-Badia, L.M. (Luis M.), Nguyen, P. (PhuongMai), Trepel, J. (Jane), Vicent, S. (Silvestre)   +11 more
core   +1 more source

Epithelial Ovarian Cancer [PDF]

, 2008
Epithelial ovarian cancer has the highest mortality rate of all gynecologic cancers (1). The majority of patients are diagnosed with advanced-stage disease and consequently have a poor prognosis (1). Despite progress in surgical approaches and chemotherapeutic regimens for ovarian cancer during the last several decades, 5-yr survival rates remain ...
Kristin K. Zorn, Ginger J. Gardner, Michael J. Birrer   +2 more
  +4 more sources

IL-36α suppresses proliferation of ovarian cancer cells

Tumor Biology, 2017
Interleukin-36α (IL-36α), also formerly known as IL-1F6, is pertaining to IL-1 family members that has been shown to play an important pro-inflammatory role in chronic immune disorders.
Lei Chang, Ruixia Guo, Zhongfu Yuan
doaj   +1 more source